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JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits significant anti-inflammatory effect while maintaining bone mineral density in mice.
Kurimoto T, Tamai I, Nakagawa T, Miyai A, Yamamoto Y, Kosugi Y, Deai K, Hata T, Ohta T, Matsushita M, Yamada T. Kurimoto T, et al. Among authors: yamada t. Eur J Pharmacol. 2021 Mar 15;895:173880. doi: 10.1016/j.ejphar.2021.173880. Epub 2021 Jan 18. Eur J Pharmacol. 2021. PMID: 33476654 Free article.
JTP-109192, a novel G protein-coupled receptor 119 agonist, prevents atherosclerosis by improving hypercholesterolaemia in congenic spontaneously hyperlipidaemic mice.
Tadaki H, Ogawa N, Yamanaka M, Motohashi Y, Sasase T, Kawai T, Toriniwa Y, Fukuda S, Ogawa N, Harada K, Ohta T, Yamada T. Tadaki H, et al. Among authors: yamada t. Clin Exp Pharmacol Physiol. 2021 Mar;48(3):381-388. doi: 10.1111/1440-1681.13423. Epub 2020 Nov 4. Clin Exp Pharmacol Physiol. 2021. PMID: 33068442 Free article.
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