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The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2.
Berg TJ, Marques C, Pantazopoulou V, Johansson E, von Stedingk K, Lindgren D, Jeannot P, Pietras EJ, Bergström T, Swartling FJ, Governa V, Bengzon J, Belting M, Axelson H, Squatrito M, Pietras A. Berg TJ, et al. Among authors: belting m. Cancer Res. 2021 Apr 15;81(8):2101-2115. doi: 10.1158/0008-5472.CAN-20-1785. Epub 2021 Jan 22. Cancer Res. 2021. PMID: 33483373
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.
Svensson KJ, Kucharzewska P, Christianson HC, Sköld S, Löfstedt T, Johansson MC, Mörgelin M, Bengzon J, Ruf W, Belting M. Svensson KJ, et al. Among authors: belting m. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13147-52. doi: 10.1073/pnas.1104261108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788507 Free PMC article.
G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.
Broselid S, Cheng B, Sjöström M, Lövgren K, Klug-De Santiago HL, Belting M, Jirström K, Malmström P, Olde B, Bendahl PO, Hartman L, Fernö M, Leeb-Lundberg LM. Broselid S, et al. Among authors: belting m. Clin Cancer Res. 2013 Apr 1;19(7):1681-92. doi: 10.1158/1078-0432.CCR-12-2376. Clin Cancer Res. 2013. PMID: 23554355
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringnér M, Mörgelin M, Bourseau-Guilmain E, Bengzon J, Belting M. Kucharzewska P, et al. Among authors: belting m. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15. Proc Natl Acad Sci U S A. 2013. PMID: 23589885 Free PMC article.
Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis.
Menard JA, Christianson HC, Kucharzewska P, Bourseau-Guilmain E, Svensson KJ, Lindqvist E, Indira Chandran V, Kjellén L, Welinder C, Bengzon J, Johansson MC, Belting M. Menard JA, et al. Among authors: belting m. Cancer Res. 2016 Aug 15;76(16):4828-40. doi: 10.1158/0008-5472.CAN-15-2831. Epub 2016 May 19. Cancer Res. 2016. PMID: 27199348
Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma.
Indira Chandran V, Welinder C, Månsson AS, Offer S, Freyhult E, Pernemalm M, Lund SM, Pedersen S, Lehtiö J, Marko-Varga G, Johansson MC, Englund E, Sundgren PC, Belting M. Indira Chandran V, et al. Among authors: belting m. Clin Cancer Res. 2019 May 15;25(10):3115-3127. doi: 10.1158/1078-0432.CCR-18-2946. Epub 2019 Jan 24. Clin Cancer Res. 2019. PMID: 30679164
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