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Mice with cleavage-resistant N-cadherin exhibit synapse anomaly in the hippocampus and outperformance in spatial learning tasks.
Asada-Utsugi M, Uemura K, Kubota M, Noda Y, Tashiro Y, Uemura TM, Yamakado H, Urushitani M, Takahashi R, Hattori S, Miyakawa T, Ageta-Ishihara N, Kobayashi K, Kinoshita M, Kinoshita A. Asada-Utsugi M, et al. Among authors: kubota m. Mol Brain. 2021 Jan 25;14(1):23. doi: 10.1186/s13041-021-00738-1. Mol Brain. 2021. PMID: 33494786 Free PMC article.
N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production.
Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A. Asada-Utsugi M, et al. Among authors: kubota m. J Neurochem. 2011 Oct;119(2):354-63. doi: 10.1111/j.1471-4159.2011.07364.x. Epub 2011 Sep 20. J Neurochem. 2011. PMID: 21699541 Free PMC article.
N-cadherin-based adhesion enhances Abeta release and decreases Abeta42/40 ratio.
Uemura K, Lill CM, Banks M, Asada M, Aoyagi N, Ando K, Kubota M, Kihara T, Nishimoto T, Sugimoto H, Takahashi R, Hyman BT, Shimohama S, Berezovska O, Kinoshita A. Uemura K, et al. Among authors: kubota m. J Neurochem. 2009 Jan;108(2):350-60. doi: 10.1111/j.1471-4159.2008.05760.x. Epub 2008 Nov 25. J Neurochem. 2009. PMID: 19046403 Free PMC article.
N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein: implications for neurodegeneration in Alzheimer disease.
Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A. Ando K, et al. Among authors: kubota m. J Biol Chem. 2011 Mar 4;286(9):7619-28. doi: 10.1074/jbc.M110.158477. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177868 Free PMC article.
Continuation of exercise is necessary to inhibit high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice.
Maesako M, Uemura K, Iwata A, Kubota M, Watanabe K, Uemura M, Noda Y, Asada-Utsugi M, Kihara T, Takahashi R, Shimohama S, Kinoshita A. Maesako M, et al. Among authors: kubota m. PLoS One. 2013 Sep 4;8(9):e72796. doi: 10.1371/journal.pone.0072796. eCollection 2013. PLoS One. 2013. PMID: 24023774 Free PMC article.
Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice.
Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Hayashida N, Asada-Utsugi M, Watanabe K, Uemura M, Kihara T, Takahashi R, Shimohama S, Kinoshita A. Maesako M, et al. Among authors: kubota m. J Biol Chem. 2012 Jun 29;287(27):23024-33. doi: 10.1074/jbc.M112.367011. Epub 2012 May 4. J Biol Chem. 2012. PMID: 22563077 Free PMC article.
High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
Maesako M, Uemura M, Tashiro Y, Sasaki K, Watanabe K, Noda Y, Ueda K, Asada-Utsugi M, Kubota M, Okawa K, Ihara M, Shimohama S, Uemura K, Kinoshita A. Maesako M, et al. Among authors: kubota m. PLoS One. 2015 Sep 28;10(9):e0131199. doi: 10.1371/journal.pone.0131199. eCollection 2015. PLoS One. 2015. PMID: 26414661 Free PMC article.
2,277 results