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CTLA4-Ig-Based Bifunctional Costimulation Inhibitor Blocks CD28 and ICOS Signaling to Prevent T Cell Priming and Effector Function.
Goenka R, Xu Z, Samayoa J, Banach D, Beam C, Bose S, Dooner G, Forsyth CM, Lu X, Medina L, Sadhukhan R, Sielaff B, Sousa S, Tao Q, Touw D, Wu F, Kingsbury GA, Akamatsu Y. Goenka R, et al. Among authors: sousa s. J Immunol. 2021 Mar 1;206(5):1102-1113. doi: 10.4049/jimmunol.2001100. Epub 2021 Jan 25. J Immunol. 2021. PMID: 33495237
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.
Argiriadi MA, Benatuil L, Dubrovska I, Egan DA, Gao L, Greischar A, Hardman J, Harlan J, Iyer RB, Judge RA, Lake M, Perron DC, Sadhukhan R, Sielaff B, Sousa S, Wang R, McRae BL. Argiriadi MA, et al. Among authors: sousa s. BMC Mol Cell Biol. 2019 Aug 5;20(1):29. doi: 10.1186/s12860-019-0213-4. BMC Mol Cell Biol. 2019. PMID: 31382872 Free PMC article.
Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Argiriadi MA, Goedken ER, Banach D, Borhani DW, Burchat A, Dixon RW, Marcotte D, Overmeyer G, Pivorunas V, Sadhukhan R, Sousa S, Moore NS, Tomlinson M, Voss J, Wang L, Wishart N, Woller K, Talanian RV. Argiriadi MA, et al. Among authors: sousa s. BMC Struct Biol. 2012 Sep 20;12:22. doi: 10.1186/1472-6807-12-22. BMC Struct Biol. 2012. PMID: 22995073 Free PMC article.
2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode.
Argiriadi MA, Ericsson AM, Harris CM, Banach DL, Borhani DW, Calderwood DJ, Demers MD, Dimauro J, Dixon RW, Hardman J, Kwak S, Li B, Mankovich JA, Marcotte D, Mullen KD, Ni B, Pietras M, Sadhukhan R, Sousa S, Tomlinson MJ, Wang L, Xiang T, Talanian RV. Argiriadi MA, et al. Among authors: sousa s. Bioorg Med Chem Lett. 2010 Jan 1;20(1):330-3. doi: 10.1016/j.bmcl.2009.10.102. Epub 2009 Oct 29. Bioorg Med Chem Lett. 2010. PMID: 19919896
Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study.
Argiriadi MA, Sousa S, Banach D, Marcotte D, Xiang T, Tomlinson MJ, Demers M, Harris C, Kwak S, Hardman J, Pietras M, Quinn L, DiMauro J, Ni B, Mankovich J, Borhani DW, Talanian RV, Sadhukhan R. Argiriadi MA, et al. Among authors: sousa s. BMC Struct Biol. 2009 Mar 18;9:16. doi: 10.1186/1472-6807-9-16. BMC Struct Biol. 2009. PMID: 19296855 Free PMC article.
Analysis of the Antibiotic-Potentiating Activity, Absorption, Distribution, Metabolism, and Excretion (ADME) and the Molecular Docking Properties of Phytol Against Multi-Drug-Resistant (MDR) Strains.
Almeida-Bezerra JW, Menezes SA, Silva JTDC, de Sousa SG, Alves DS, Alencar GG, Araújo IM, Rodrigues EYS, Oliveira-Tintino CDM, da Cruz RP, Rocha JE, Tintino SR, Barbosa-Filho JM, Morais-Braga MFB, de Menezes IRA, Raposo A, Coutinho HDM. Almeida-Bezerra JW, et al. Among authors: de sousa sg. Antibiotics (Basel). 2024 Dec 4;13(12):1171. doi: 10.3390/antibiotics13121171. Antibiotics (Basel). 2024. PMID: 39766561 Free PMC article.
1,355 results