Biechele TL - Search Results

1

Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness.

Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M. Cheng J, et al. Among authors: biechele tl. Cell Chem Biol. 2021 May 20;28(5):625-635.e5. doi: 10.1016/j.chembiol.2021.01.001. Epub 2021 Jan 26. Cell Chem Biol. 2021. PMID: 33503403 Free PMC article.

2

Assaying beta-catenin/TCF transcription with beta-catenin/TCF transcription-based reporter constructs.

Biechele TL, Moon RT. Biechele TL, et al. Methods Mol Biol. 2008;468:99-110. doi: 10.1007/978-1-59745-249-6_8. Methods Mol Biol. 2008. PMID: 19099249

3

Transcription-based reporters of Wnt/beta-catenin signaling.

Biechele TL, Adams AM, Moon RT. Biechele TL, et al. Cold Spring Harb Protoc. 2009 Jun;2009(6):pdb.prot5223. doi: 10.1101/pdb.prot5223. Cold Spring Harb Protoc. 2009. PMID: 20147181 No abstract available.

4

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. Angers S, et al. Among authors: biechele tl. Nat Cell Biol. 2006 Apr;8(4):348-57. doi: 10.1038/ncb1381. Epub 2006 Mar 19. Nat Cell Biol. 2006. PMID: 16547521

5

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Conrad WH, et al. Among authors: biechele tl. Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22895053 Free PMC article.

6

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4.

Davidson KC, Adams AM, Goodson JM, McDonald CE, Potter JC, Berndt JD, Biechele TL, Taylor RJ, Moon RT. Davidson KC, et al. Among authors: biechele tl. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4485-90. doi: 10.1073/pnas.1118777109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22392999 Free PMC article.

7

Integrative analysis of genome-wide RNA interference screens.

Berndt JD, Biechele TL, Moon RT, Major MB. Berndt JD, et al. Among authors: biechele tl. Sci Signal. 2009 May 12;2(70):pt4. doi: 10.1126/scisignal.270pt4. Sci Signal. 2009. PMID: 19436058

8

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.

James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: biechele tl. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.

9

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Biechele TL, et al. Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274. Sci Signal. 2012. PMID: 22234612 Free PMC article.

10

WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling.

James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT. James RG, et al. Among authors: biechele tl. PLoS One. 2012;7(12):e50457. doi: 10.1371/journal.pone.0050457. Epub 2012 Dec 5. PLoS One. 2012. PMID: 23227175 Free PMC article.

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