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Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant.
Annunziato G, Spadini C, Franko N, Storici P, Demitri N, Pieroni M, Flisi S, Rosati L, Iannarelli M, Marchetti M, Magalhaes J, Bettati S, Mozzarelli A, Cabassi CS, Campanini B, Costantino G. Annunziato G, et al. Among authors: costantino g. ACS Infect Dis. 2021 Feb 12;7(2):281-292. doi: 10.1021/acsinfecdis.0c00378. Epub 2021 Jan 29. ACS Infect Dis. 2021. PMID: 33513010
Rational Design, Synthesis, and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O-Acetylserine Sulfhydrylase.
Pieroni M, Annunziato G, Beato C, Wouters R, Benoni R, Campanini B, Pertinhez TA, Bettati S, Mozzarelli A, Costantino G. Pieroni M, et al. Among authors: costantino g. J Med Chem. 2016 Mar 24;59(6):2567-78. doi: 10.1021/acs.jmedchem.5b01775. Epub 2016 Mar 2. J Med Chem. 2016. PMID: 26894308
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR.
Annunziato G, Pieroni M, Benoni R, Campanini B, Pertinhez TA, Pecchini C, Bruno A, Magalhães J, Bettati S, Franko N, Mozzarelli A, Costantino G. Annunziato G, et al. Among authors: costantino g. J Enzyme Inhib Med Chem. 2016;31(sup4):78-87. doi: 10.1080/14756366.2016.1218486. Epub 2016 Aug 31. J Enzyme Inhib Med Chem. 2016. PMID: 27578398 Free article.
565 results