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HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.
Philip K, Mills TW, Davies J, Chen NY, Karmouty-Quintana H, Luo F, Molina JG, Amione-Guerra J, Sinha N, Guha A, Eltzschig HK, Blackburn MR. Philip K, et al. FASEB J. 2017 Nov;31(11):4745-4758. doi: 10.1096/fj.201700219R. Epub 2017 Jul 12. FASEB J. 2017. PMID: 28701304 Free PMC article.
These studies support a potential role for HIF1A or ADORA2B antagonists in the treatment of IPF.-Philip, K., Mills, T. W., Davies, J., Chen, N.-Y., Karmouty-Quintana, H., Luo, F., Molina, J. G., Amione-Guerra, J., Sinha, N., Guha, A., Eltzschig, H. ...
These studies support a potential role for HIF1A or ADORA2B antagonists in the treatment of IPF.-Philip, K., Mills, T. W., Dav …
Editorial: Purinergic Signaling and Inflammation.
Yuan X, Ferrari D, Mills T, Wang Y, Czopik A, Doursout MF, Evans SE, Idzko M, Eltzschig HK. Yuan X, et al. Among authors: mills t. Front Immunol. 2021 May 19;12:699069. doi: 10.3389/fimmu.2021.699069. eCollection 2021. Front Immunol. 2021. PMID: 34093597 Free PMC article. No abstract available.
SARS-CoV-2 Infection: Host Response, Immunity, and Therapeutic Targets.
Shivshankar P, Karmouty-Quintana H, Mills T, Doursout MF, Wang Y, Czopik AK, Evans SE, Eltzschig HK, Yuan X. Shivshankar P, et al. Among authors: mills t. Inflammation. 2022 Aug;45(4):1430-1449. doi: 10.1007/s10753-022-01656-7. Epub 2022 Mar 23. Inflammation. 2022. PMID: 35320469 Free PMC article. Review.
Alternative adenosine Receptor activation: The netrin-Adora2b link.
Yuan X, Mills T, Doursout MF, Evans SE, Vidal Melo MF, Eltzschig HK. Yuan X, et al. Among authors: mills t. Front Pharmacol. 2022 Jul 15;13:944994. doi: 10.3389/fphar.2022.944994. eCollection 2022. Front Pharmacol. 2022. PMID: 35910389 Free PMC article. Review.
565 results