Esser-Kahn AP - Search Results

1

Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands.

Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Kimani FW, et al. ACS Chem Biol. 2021 Feb 19;16(2):380-388. doi: 10.1021/acschembio.0c00924. Epub 2021 Feb 1. ACS Chem Biol. 2021. PMID: 33523635 Free PMC article.

2

Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation.

Tom JK, Mancini RJ, Esser-Kahn AP. Tom JK, et al. Chem Commun (Camb). 2013 Oct 25;49(83):9618-20. doi: 10.1039/c3cc45468a. Chem Commun (Camb). 2013. PMID: 24022092 Free PMC article.

3

Directing the immune system with chemical compounds.

Mancini RJ, Stutts L, Ryu KA, Tom JK, Esser-Kahn AP. Mancini RJ, et al. ACS Chem Biol. 2014 May 16;9(5):1075-85. doi: 10.1021/cb500079s. Epub 2014 Apr 30. ACS Chem Biol. 2014. PMID: 24690004 Free PMC article. Review.

4

Stimulation of innate immune cells by light-activated TLR7/8 agonists.

Ryu KA, Stutts L, Tom JK, Mancini RJ, Esser-Kahn AP. Ryu KA, et al. J Am Chem Soc. 2014 Aug 6;136(31):10823-5. doi: 10.1021/ja412314j. Epub 2014 Jul 28. J Am Chem Soc. 2014. PMID: 25029205 Free PMC article.

5

Modulation of Innate Immune Responses via Covalently Linked TLR Agonists.

Tom JK, Dotsey EY, Wong HY, Stutts L, Moore T, Davies DH, Felgner PL, Esser-Kahn AP. Tom JK, et al. ACS Cent Sci. 2015 Nov 25;1(8):439-448. doi: 10.1021/acscentsci.5b00274. Epub 2015 Oct 28. ACS Cent Sci. 2015. PMID: 26640818 Free PMC article.

6

Immune Response Modulation of Conjugated Agonists with Changing Linker Length.

Ryu KA, Slowinska K, Moore T, Esser-Kahn A. Ryu KA, et al. ACS Chem Biol. 2016 Dec 16;11(12):3347-3352. doi: 10.1021/acschembio.6b00895. Epub 2016 Oct 25. ACS Chem Biol. 2016. PMID: 27749034 Free PMC article.

7

A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation.

Moser BA, Esser-Kahn AP. Moser BA, et al. ACS Chem Biol. 2017 Feb 17;12(2):347-350. doi: 10.1021/acschembio.6b01012. Epub 2016 Dec 29. ACS Chem Biol. 2017. PMID: 28000442 Free PMC article.

8

Toll-like Receptor Agonist Conjugation: A Chemical Perspective.

Ignacio BJ, Albin TJ, Esser-Kahn AP, Verdoes M. Ignacio BJ, et al. Bioconjug Chem. 2018 Mar 21;29(3):587-603. doi: 10.1021/acs.bioconjchem.7b00808. Epub 2018 Feb 16. Bioconjug Chem. 2018. PMID: 29378134 Free PMC article. Review.

9

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture.

Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Manna S, et al. ACS Cent Sci. 2018 Aug 22;4(8):982-995. doi: 10.1021/acscentsci.8b00218. Epub 2018 Jul 2. ACS Cent Sci. 2018. PMID: 30159395 Free PMC article.

10

Applications of Immunomodulatory Immune Synergies to Adjuvant Discovery and Vaccine Development.

Tom JK, Albin TJ, Manna S, Moser BA, Steinhardt RC, Esser-Kahn AP. Tom JK, et al. Trends Biotechnol. 2019 Apr;37(4):373-388. doi: 10.1016/j.tibtech.2018.10.004. Epub 2018 Nov 21. Trends Biotechnol. 2019. PMID: 30470547 Review.

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