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Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.
Tamai T, Yamaguchi O, Hikoso S, Takeda T, Taneike M, Oka T, Oyabu J, Murakawa T, Nakayama H, Uno Y, Horie K, Nishida K, Sonenberg N, Shah AM, Takeda J, Komuro I, Otsu K. Tamai T, et al. Among authors: shah am. J Biol Chem. 2013 Apr 5;288(14):10176-10187. doi: 10.1074/jbc.M112.423640. Epub 2013 Feb 20. J Biol Chem. 2013. PMID: 23426372 Free PMC article.
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.
Murakawa T, Yamaguchi O, Hashimoto A, Hikoso S, Takeda T, Oka T, Yasui H, Ueda H, Akazawa Y, Nakayama H, Taneike M, Misaka T, Omiya S, Shah AM, Yamamoto A, Nishida K, Ohsumi Y, Okamoto K, Sakata Y, Otsu K. Murakawa T, et al. Among authors: shah am. Nat Commun. 2015 Jul 6;6:7527. doi: 10.1038/ncomms8527. Nat Commun. 2015. PMID: 26146385 Free PMC article.
mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.
Taneike M, Nishida K, Omiya S, Zarrinpashneh E, Misaka T, Kitazume-Taneike R, Austin R, Takaoka M, Yamaguchi O, Gambello MJ, Shah AM, Otsu K. Taneike M, et al. Among authors: shah am. PLoS One. 2016 Mar 29;11(3):e0152628. doi: 10.1371/journal.pone.0152628. eCollection 2016. PLoS One. 2016. PMID: 27023784 Free PMC article.
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M. Barallobre-Barreiro J, et al. Among authors: shah am. Circulation. 2016 Sep 13;134(11):817-32. doi: 10.1161/CIRCULATIONAHA.115.016423. Epub 2016 Aug 24. Circulation. 2016. PMID: 27559042 Free PMC article.
Hypoxia induces heart regeneration in adult mice.
Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA. Nakada Y, et al. Among authors: shah am. Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31. Nature. 2017. PMID: 27798600
FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice.
Misaka T, Murakawa T, Nishida K, Omori Y, Taneike M, Omiya S, Molenaar C, Uno Y, Yamaguchi O, Takeda J, Shah AM, Otsu K. Misaka T, et al. Among authors: shah am. J Mol Cell Cardiol. 2018 Jan;114:93-104. doi: 10.1016/j.yjmcc.2017.11.004. Epub 2017 Nov 10. J Mol Cell Cardiol. 2018. PMID: 29129702 Free PMC article.
1,051 results