Arvan P - Search Results

1

Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size.

Sui L, Xin Y, Du Q, Georgieva D, Diedenhofen G, Haataja L, Su Q, Zuccaro MV, Kim J, Fu J, Xing Y, He Y, Baum D, Goland RS, Wang Y, Oberholzer J, Barbetti F, Arvan P, Kleiner S, Egli D. Sui L, et al. Among authors: arvan p. JCI Insight. 2021 Mar 8;6(5):e141553. doi: 10.1172/jci.insight.141553. JCI Insight. 2021. PMID: 33529174 Free PMC article.

2

Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.

Colombo C, Porzio O, Liu M, Massa O, Vasta M, Salardi S, Beccaria L, Monciotti C, Toni S, Pedersen O, Hansen T, Federici L, Pesavento R, Cadario F, Federici G, Ghirri P, Arvan P, Iafusco D, Barbetti F; Early Onset Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (SIEDP). Colombo C, et al. Among authors: arvan p. J Clin Invest. 2008 Jun;118(6):2148-56. doi: 10.1172/JCI33777. J Clin Invest. 2008. PMID: 18451997 Free PMC article.

3

Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.

Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P. Liu M, et al. Among authors: arvan p. Trends Endocrinol Metab. 2010 Nov;21(11):652-9. doi: 10.1016/j.tem.2010.07.001. Epub 2010 Aug 18. Trends Endocrinol Metab. 2010. PMID: 20724178 Free PMC article. Review.

4

Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.

Liu M, Haataja L, Wright J, Wickramasinghe NP, Hua QX, Phillips NF, Barbetti F, Weiss MA, Arvan P. Liu M, et al. Among authors: arvan p. PLoS One. 2010 Oct 11;5(10):e13333. doi: 10.1371/journal.pone.0013333. PLoS One. 2010. PMID: 20948967 Free PMC article.

5

In vivo misfolding of proinsulin below the threshold of frank diabetes.

Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. Hodish I, et al. Among authors: arvan p. Diabetes. 2011 Aug;60(8):2092-101. doi: 10.2337/db10-1671. Epub 2011 Jun 15. Diabetes. 2011. PMID: 21677281 Free PMC article.

6

Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes.

Liu M, Lara-Lemus R, Shan SO, Wright J, Haataja L, Barbetti F, Guo H, Larkin D, Arvan P. Liu M, et al. Among authors: arvan p. Diabetes. 2012 Apr;61(4):828-37. doi: 10.2337/db11-0878. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357960 Free PMC article.

7

Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells.

Haataja L, Snapp E, Wright J, Liu M, Hardy AB, Wheeler MB, Markwardt ML, Rizzo MA, Arvan P. Haataja L, et al. Among authors: arvan p. J Biol Chem. 2013 Jan 18;288(3):1896-906. doi: 10.1074/jbc.M112.420018. Epub 2012 Dec 6. J Biol Chem. 2013. PMID: 23223446 Free PMC article.

8

Dominant protein interactions that influence the pathogenesis of conformational diseases.

Wright J, Wang X, Haataja L, Kellogg AP, Lee J, Liu M, Arvan P. Wright J, et al. Among authors: arvan p. J Clin Invest. 2013 Jul;123(7):3124-34. doi: 10.1172/JCI67260. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722904 Free PMC article.

9

Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.

Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P. Wright J, et al. Among authors: arvan p. J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022479 Free PMC article.

10

Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.

Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Guo H, et al. Among authors: arvan p. J Biol Chem. 2014 Jun 6;289(23):16290-302. doi: 10.1074/jbc.M114.562355. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770419 Free PMC article.

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