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Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.
González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, Egli D. González BJ, et al. Among authors: goland rs. Commun Biol. 2022 Aug 2;5(1):779. doi: 10.1038/s42003-022-03696-z. Commun Biol. 2022. PMID: 35918471 Free PMC article.
Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos.
Zuccaro MV, Xu J, Mitchell C, Marin D, Zimmerman R, Rana B, Weinstein E, King RT, Palmerola KL, Smith ME, Tsang SH, Goland R, Jasin M, Lobo R, Treff N, Egli D. Zuccaro MV, et al. Cell. 2020 Dec 10;183(6):1650-1664.e15. doi: 10.1016/j.cell.2020.10.025. Epub 2020 Oct 29. Cell. 2020. PMID: 33125898 Free article.
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons.
Wang L, Liu Y, Stratigopoulos G, Panigrahi S, Sui L, Zhang Y, Leduc CA, Glover HJ, De Rosa MC, Burnett LC, Williams DJ, Shang L, Goland R, Tsang SH, Wardlaw S, Egli D, Zheng D, Doege CA, Leibel RL. Wang L, et al. J Clin Invest. 2021 Apr 15;131(8):e146287. doi: 10.1172/JCI146287. J Clin Invest. 2021. PMID: 33630762 Free PMC article.
Human oocytes reprogram somatic cells to a pluripotent state.
Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, Egli D. Noggle S, et al. Nature. 2011 Oct 5;478(7367):70-5. doi: 10.1038/nature10397. Nature. 2011. PMID: 21979046
171 results