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Mechanism of cancer: Oncohistones in action.
Qiu L, Hu X, Jing Q, Zeng X, Chan KM, Han J. Qiu L, et al. Among authors: han j. J Genet Genomics. 2018 May 20;45(5):227-236. doi: 10.1016/j.jgg.2018.04.004. Epub 2018 Apr 30. J Genet Genomics. 2018. PMID: 29804713 Review.
Rtt105 functions as a chaperone for replication protein A to preserve genome stability.
Li S, Xu Z, Xu J, Zuo L, Yu C, Zheng P, Gan H, Wang X, Li L, Sharma S, Chabes A, Li D, Wang S, Zheng S, Li J, Chen X, Sun Y, Xu D, Han J, Chan K, Qi Z, Feng J, Li Q. Li S, et al. Among authors: han j. EMBO J. 2018 Sep 3;37(17):e99154. doi: 10.15252/embj.201899154. Epub 2018 Jul 31. EMBO J. 2018. PMID: 30065069 Free PMC article.
Cancer-associated histone mutation H2BG53D disrupts DNA-histone octamer interaction and promotes oncogenic phenotypes.
Wan YCE, Leung TCS, Ding D, Sun X, Liu J, Zhu L, Kang TZE, Yang D, Zhang Y, Zhang J, Qian C, Huen MSY, Li Q, Chow MZY, Zheng Z, Han J, Goel A, Wang X, Ishibashi T, Chan KM. Wan YCE, et al. Among authors: han j. Signal Transduct Target Ther. 2020 Mar 6;5(1):27. doi: 10.1038/s41392-020-0131-0. Signal Transduct Target Ther. 2020. PMID: 32296031 Free PMC article. No abstract available.
DNA polymerase delta governs parental histone transfer to DNA replication lagging strand.
Tian C, Zhang Q, Jia J, Zhou J, Zhang Z, Karri S, Jiang J, Dickinson Q, Yao Y, Tang X, Huang Y, Guo T, He Z, Liu Z, Gao Y, Yang X, Wu Y, Chan KM, Zhang D, Han J, Yu C, Gan H. Tian C, et al. Among authors: han j. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2400610121. doi: 10.1073/pnas.2400610121. Epub 2024 May 7. Proc Natl Acad Sci U S A. 2024. PMID: 38713623 Free PMC article.
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