Liu X - Search Results

1

Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding.

Liu X, Suyama K, Nose T, Shimohigashi M, Shimohigashi Y. Liu X, et al. PLoS One. 2021 Feb 9;16(2):e0246583. doi: 10.1371/journal.pone.0246583. eCollection 2021. PLoS One. 2021. PMID: 33561155 Free PMC article.

2

Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity.

Takayanagi S, Tokunaga T, Liu X, Okada H, Matsushima A, Shimohigashi Y. Takayanagi S, et al. Among authors: liu x. Toxicol Lett. 2006 Dec 1;167(2):95-105. doi: 10.1016/j.toxlet.2006.08.012. Epub 2006 Sep 3. Toxicol Lett. 2006. PMID: 17049190

3

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma.

Matsushima A, Kakuta Y, Teramoto T, Koshiba T, Liu X, Okada H, Tokunaga T, Kawabata S, Kimura M, Shimohigashi Y. Matsushima A, et al. Among authors: liu x. J Biochem. 2007 Oct;142(4):517-24. doi: 10.1093/jb/mvm158. Epub 2007 Aug 30. J Biochem. 2007. PMID: 17761695

4

Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor gamma. Chief and corroborative hydrogen bonds of the bisphenol A phenol-hydroxyl group with Arg316 and Glu275 residues.

Liu X, Matsushima A, Okada H, Tokunaga T, Isozaki K, Shimohigashi Y. Liu X, et al. FEBS J. 2007 Dec;274(24):6340-51. doi: 10.1111/j.1742-4658.2007.06152.x. Epub 2007 Nov 12. FEBS J. 2007. PMID: 18005256 Free article.

5

Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma.

Okada H, Tokunaga T, Liu X, Takayanagi S, Matsushima A, Shimohigashi Y. Okada H, et al. Among authors: liu x. Environ Health Perspect. 2008 Jan;116(1):32-8. doi: 10.1289/ehp.10587. Environ Health Perspect. 2008. PMID: 18197296 Free PMC article.

6

ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner.

Matsushima A, Teramoto T, Okada H, Liu X, Tokunaga T, Kakuta Y, Shimohigashi Y. Matsushima A, et al. Among authors: liu x. Biochem Biophys Res Commun. 2008 Aug 29;373(3):408-13. doi: 10.1016/j.bbrc.2008.06.050. Epub 2008 Jun 26. Biochem Biophys Res Commun. 2008. PMID: 18582436

7

Placenta expressing the greatest quantity of bisphenol A receptor ERR{gamma} among the human reproductive tissues: Predominant expression of type-1 ERRgamma isoform.

Takeda Y, Liu X, Sumiyoshi M, Matsushima A, Shimohigashi M, Shimohigashi Y. Takeda Y, et al. Among authors: liu x. J Biochem. 2009 Jul;146(1):113-22. doi: 10.1093/jb/mvp049. Epub 2009 Mar 20. J Biochem. 2009. PMID: 19304792

8

Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta.

Matsushima A, Liu X, Okada H, Shimohigashi M, Shimohigashi Y. Matsushima A, et al. Among authors: liu x. Environ Health Perspect. 2010 Sep;118(9):1267-72. doi: 10.1289/ehp.0901819. Epub 2010 Apr 28. Environ Health Perspect. 2010. PMID: 20427257 Free PMC article.

9

Distinction of the binding modes for human nuclear receptor ERRgamma between bisphenol A and 4-hydroxytamoxifen.

Liu X, Matsushima A, Okada H, Shimohigashi Y. Liu X, et al. J Biochem. 2010 Aug;148(2):247-54. doi: 10.1093/jb/mvq056. Epub 2010 Jun 11. J Biochem. 2010. PMID: 20542892

10

Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol A in the human nuclear receptor estrogen-related receptor γ.

Liu X, Matsushima A, Nakamura M, Costa T, Nose T, Shimohigashi Y. Liu X, et al. J Biochem. 2012 Apr;151(4):403-15. doi: 10.1093/jb/mvs008. Epub 2012 Jan 31. J Biochem. 2012. PMID: 22298789

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