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Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts.
Le Manach C, Dam J, Woodland JG, Kaur G, Khonde LP, Brunschwig C, Njoroge M, Wicht KJ, Horatscheck A, Paquet T, Boyle GA, Gibhard L, Taylor D, Lawrence N, Yeo T, Mok S, Eastman RT, Dorjsuren D, Talley DC, Guo H, Simeonov A, Reader J, van der Watt M, Erlank E, Venter N, Zawada JW, Aswat A, Nardini L, Coetzer TL, Lauterbach SB, Bezuidenhout BC, Theron A, Mancama D, Koekemoer LL, Birkholtz LM, Wittlin S, Delves M, Ottilie S, Winzeler EA, von Geldern TW, Smith D, Fidock DA, Street LJ, Basarab GS, Duffy J, Chibale K. Le Manach C, et al. Among authors: zawada jw. J Med Chem. 2021 Feb 25;64(4):2291-2309. doi: 10.1021/acs.jmedchem.1c00034. Epub 2021 Feb 12. J Med Chem. 2021. PMID: 33573376
Male swarming aggregation pheromones increase female attraction and mating success among multiple African malaria vector mosquito species.
Mozūraitis R, Hajkazemian M, Zawada JW, Szymczak J, Pålsson K, Sekar V, Biryukova I, Friedländer MR, Koekemoer LL, Baird JK, Borg-Karlson AK, Emami SN. Mozūraitis R, et al. Among authors: zawada jw. Nat Ecol Evol. 2020 Oct;4(10):1395-1401. doi: 10.1038/s41559-020-1264-9. Epub 2020 Aug 3. Nat Ecol Evol. 2020. PMID: 32747772
Comparison of the effect of bacterial stimulation on the global epigenetic landscape and transcription of immune genes in primarily zoophilic members of the Anopheles gambiae complex (Diptera: Culicidae).
Patel NF, Letinić BD, Lobb L, Zawada J, Dlamini DM, Mabaso N, Munhenga G, Oliver SV. Patel NF, et al. Mol Biochem Parasitol. 2024 Dec;260:111631. doi: 10.1016/j.molbiopara.2024.111631. Epub 2024 Jun 4. Mol Biochem Parasitol. 2024. PMID: 38844266 Free PMC article.