Lindholm HT - Search Results

1

A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation.

Ostrop J, Zwiggelaar RT, Terndrup Pedersen M, Gerbe F, Bösl K, Lindholm HT, Díez-Sánchez A, Parmar N, Radetzki S, von Kries JP, Jay P, Jensen KB, Arrowsmith C, Oudhoff MJ. Ostrop J, et al. Among authors: lindholm ht. Front Cell Dev Biol. 2021 Jan 21;8:618552. doi: 10.3389/fcell.2020.618552. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33575256 Free PMC article.

2

LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.

Zwiggelaar RT, Lindholm HT, Fosslie M, Terndrup Pedersen M, Ohta Y, Díez-Sánchez A, Martín-Alonso M, Ostrop J, Matano M, Parmar N, Kvaløy E, Spanjers RR, Nazmi K, Rye M, Drabløs F, Arrowsmith C, Arne Dahl J, Jensen KB, Sato T, Oudhoff MJ. Zwiggelaar RT, et al. Among authors: lindholm ht. Sci Adv. 2020 Sep 11;6(37):eabc0367. doi: 10.1126/sciadv.abc0367. Print 2020 Sep. Sci Adv. 2020. PMID: 32917713 Free PMC article.

3

Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.

Parmar N, Burrows K, Vornewald PM, Lindholm HT, Zwiggelaar RT, Díez-Sánchez A, Martín-Alonso M, Fosslie M, Vallance BA, Dahl JA, Zaph C, Oudhoff MJ. Parmar N, et al. Among authors: lindholm ht. PLoS Pathog. 2021 Mar 31;17(3):e1009476. doi: 10.1371/journal.ppat.1009476. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33788902 Free PMC article.

4

Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products.

Drurey C, Lindholm HT, Coakley G, Poveda MC, Löser S, Doolan R, Gerbe F, Jay P, Harris N, Oudhoff MJ, Maizels RM. Drurey C, et al. Among authors: lindholm ht. J Exp Med. 2022 Jan 3;219(1):e20211140. doi: 10.1084/jem.20211140. Epub 2021 Nov 15. J Exp Med. 2022. PMID: 34779829 Free PMC article.

5

Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage.

Martín-Alonso M, Iqbal S, Vornewald PM, Lindholm HT, Damen MJ, Martínez F, Hoel S, Díez-Sánchez A, Altelaar M, Katajisto P, Arroyo AG, Oudhoff MJ. Martín-Alonso M, et al. Among authors: lindholm ht. Nat Commun. 2021 Nov 18;12(1):6741. doi: 10.1038/s41467-021-26904-6. Nat Commun. 2021. PMID: 34795242 Free PMC article.

6

BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13-driven tuft cell hyperplasia.

Lindholm HT, Parmar N, Drurey C, Campillo Poveda M, Vornewald PM, Ostrop J, Díez-Sanchez A, Maizels RM, Oudhoff MJ. Lindholm HT, et al. Sci Immunol. 2022 May 13;7(71):eabl6543. doi: 10.1126/sciimmunol.abl6543. Epub 2022 May 13. Sci Immunol. 2022. PMID: 35559665 Free PMC article.

7

Mmp17-deficient mice exhibit heightened goblet cell effector expression in the colon and increased resistance to chronic Trichuris muris infection.

Vornewald PM, Forman R, Yao R, Parmar N, Lindholm HT, Lee LSK, Martín-Alonso M, Else KJ, Oudhoff MJ. Vornewald PM, et al. Among authors: lindholm ht. Front Immunol. 2023 Oct 6;14:1243528. doi: 10.3389/fimmu.2023.1243528. eCollection 2023. Front Immunol. 2023. PMID: 37869014 Free PMC article.

8

LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model.

Díez-Sánchez A, Lindholm HT, Vornewald PM, Ostrop J, Yao R, Single AB, Marstad A, Parmar N, Shaw TN, Martín-Alonso M, Oudhoff MJ. Díez-Sánchez A, et al. Among authors: lindholm ht. Nat Commun. 2024 Apr 22;15(1):3412. doi: 10.1038/s41467-024-47815-2. Nat Commun. 2024. PMID: 38649356 Free PMC article.

9

Differentially Expressed Extracellular Vesicle-Contained microRNAs before and after Transurethral Resection of Bladder Tumors.

Strømme O, Heck KA, Brede G, Lindholm HT, Otterlei M, Arum CJ. Strømme O, et al. Among authors: lindholm ht. Curr Issues Mol Biol. 2021 Jun 4;43(1):286-300. doi: 10.3390/cimb43010024. Curr Issues Mol Biol. 2021. PMID: 34199766 Free PMC article.

10

Characterisation of Colorectal Cancer Cell Lines through Proteomic Profiling of Their Extracellular Vesicles.

Heck KA, Lindholm HT, Niederdorfer B, Tsirvouli E, Kuiper M, Flobak Å, Lægreid A, Thommesen L. Heck KA, et al. Among authors: lindholm ht. Proteomes. 2023 Jan 11;11(1):3. doi: 10.3390/proteomes11010003. Proteomes. 2023. PMID: 36648961 Free PMC article.

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