Gray D - Search Results

1

Dopamine D₁ Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates.

Barret O, Zhang L, Alagille D, Constantinescu CC, Sandiego C, Papin C, Sullivan JM, Morley T, Carroll VM, Seibyl J, Chen J, Lee C, Villalobos A, Gray D, McCarthy TJ, Tamagnan G. Barret O, et al. Among authors: gray d. J Nucl Med. 2021 Sep 1;62(9):1307-1313. doi: 10.2967/jnumed.120.256008. Epub 2021 Feb 12. J Nucl Med. 2021. PMID: 33579806 Free PMC article.

2

A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex.

Wang M, Datta D, Enwright J, Galvin V, Yang ST, Paspalas C, Kozak R, Gray DL, Lewis DA, Arnsten AFT. Wang M, et al. Among authors: gray dl. Neuropharmacology. 2019 May 15;150:46-58. doi: 10.1016/j.neuropharm.2019.03.001. Epub 2019 Mar 8. Neuropharmacology. 2019. PMID: 30858103 Free PMC article.

3

Dopamine D1 receptor-agonist interactions: A mutagenesis and homology modeling study.

Mente S, Guilmette E, Salafia M, Gray D. Mente S, et al. Among authors: gray d. Bioorg Med Chem Lett. 2015;25(10):2106-11. doi: 10.1016/j.bmcl.2015.03.079. Epub 2015 Mar 31. Bioorg Med Chem Lett. 2015. PMID: 25881819

4

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor.

Gray DL, Allen JA, Mente S, O'Connor RE, DeMarco GJ, Efremov I, Tierney P, Volfson D, Davoren J, Guilmette E, Salafia M, Kozak R, Ehlers MD. Gray DL, et al. Nat Commun. 2018 Feb 14;9(1):674. doi: 10.1038/s41467-017-02776-7. Nat Commun. 2018. PMID: 29445200 Free PMC article.

5

A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/D5 receptor partial agonist (PF-06412562) in patients with stable schizophrenia.

Arce E, Balice-Gordon R, Duvvuri S, Naylor M, Xie Z, Harel B, Kozak R, Gray DL, DeMartinis N. Arce E, et al. J Psychopharmacol. 2019 Oct;33(10):1237-1247. doi: 10.1177/0269881119855302. Epub 2019 Jul 2. J Psychopharmacol. 2019. PMID: 31264510 Clinical Trial.

6

D1 Agonist Improved Movement of Parkinsonian Nonhuman Primates with Limited Dyskinesia Side Effects.

Young D, Popiolek M, Trapa P, Fonseca KR, Brevard J, Gray DL, Kozak R. Young D, et al. Among authors: gray dl. ACS Chem Neurosci. 2020 Feb 19;11(4):560-566. doi: 10.1021/acschemneuro.9b00589. Epub 2020 Feb 6. ACS Chem Neurosci. 2020. PMID: 31971364

7

Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation.

Kozak R, Kiss T, Dlugolenski K, Johnson DE, Gorczyca RR, Kuszpit K, Harvey BD, Stolyar P, Sukoff Rizzo SJ, Hoffmann WE, Volfson D, Hajós M, Davoren JE, Abbott AL, Williams GV, Castner SA, Gray DL. Kozak R, et al. Among authors: gray dl. Front Pharmacol. 2020 Jul 7;11:1005. doi: 10.3389/fphar.2020.01005. eCollection 2020. Front Pharmacol. 2020. PMID: 32733245 Free PMC article.

8

Mechanism-based pharmacokinetic/pharmacodynamic modeling of rat prefrontal cortical dopamine response to dual acting norepinephrine reuptake inhibitor and 5-HT1A partial agonist.

Li CS, Zhang L, Haske T, Dounay A, Gray D, Barta N, Brodfuehrer J, Lepsy C, Campbell B. Li CS, et al. Among authors: gray d. AAPS J. 2012 Jun;14(2):365-76. doi: 10.1208/s12248-012-9343-8. Epub 2012 Mar 28. AAPS J. 2012. PMID: 22454087 Free PMC article.

9

Dopaminergic D₁ Receptor Stimulation Affects Effort and Risk Preferences.

Soutschek A, Gvozdanovic G, Kozak R, Duvvuri S, de Martinis N, Harel B, Gray DL, Fehr E, Jetter A, Tobler PN. Soutschek A, et al. Biol Psychiatry. 2020 Apr 1;87(7):678-685. doi: 10.1016/j.biopsych.2019.09.002. Epub 2019 Sep 12. Biol Psychiatry. 2020. PMID: 31668477 Free article. Clinical Trial.

10

The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey.

Moore TL, Young DA, Killiany RJ, Fonseca KR, Volfson D, Gray DL, Balice-Gordon R, Kozak R. Moore TL, et al. Among authors: gray dl. Front Aging Neurosci. 2021 Nov 26;13:757850. doi: 10.3389/fnagi.2021.757850. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34899271 Free PMC article.

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