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Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators.
Hou J, Wang Y, Shi L, Chen Y, Xu C, Saeedi A, Pan K, Bohat R, Egan NA, McKenzie JA, Mbofung RM, Williams LJ, Yang Z, Sun M, Liang X, Rodon Ahnert J, Varadarajan N, Yee C, Chen Y, Hwu P, Peng W. Hou J, et al. Among authors: egan na. J Immunother Cancer. 2021 Feb;9(2):e001819. doi: 10.1136/jitc-2020-001819. J Immunother Cancer. 2021. PMID: 33589527 Free PMC article.
Faslpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus.
Bohat R, Liang X, Chen Y, Xu C, Zheng N, Guerrero A, Hou J, Jaffery R, Egan NA, Li Y, Tang Y, Unsal E, Robles A, Chen S, Major AM, Elldakli H, Chung SH, Liang H, Hicks MJ, Du Y, Lin JS, Chen X, Mohan C, Peng W. Bohat R, et al. Among authors: egan na. Clin Immunol. 2024 Jan;258:109874. doi: 10.1016/j.clim.2023.109874. Epub 2023 Dec 17. Clin Immunol. 2024. PMID: 38113962 Free article.
MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors.
Chen S, Hou J, Jaffery R, Guerrero A, Fu R, Shi L, Zheng N, Bohat R, Egan NA, Yu C, Sharif S, Lu Y, He W, Wang S, Gjuka D, Stone EM, Shah PA, Rodon Ahnert J, Chen T, Liu X, Bedford MT, Xu H, Peng W. Chen S, et al. Among authors: egan na. J Immunother Cancer. 2024 Sep 23;12(9):e009600. doi: 10.1136/jitc-2024-009600. J Immunother Cancer. 2024. PMID: 39313308 Free PMC article.
Comparison of exosomes purified via ultracentrifugation (UC) and Total Exosome Isolation (TEI) reagent from the serum of Marek's disease virus (MDV)-vaccinated and tumor-bearing chickens.
Nath Neerukonda S, Egan NA, Patria J, Assakhi I, Tavlarides-Hontz P, Modla S, Muñoz ER, Hudson MB, Parcells MS. Nath Neerukonda S, et al. Among authors: egan na. J Virol Methods. 2019 Jan;263:1-9. doi: 10.1016/j.jviromet.2018.10.004. Epub 2018 Oct 11. J Virol Methods. 2019. PMID: 30316797