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Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
Yoshida S, Wei X, Zhang G, O'Connor CL, Torres M, Zhou Z, Lin L, Menon R, Xu X, Zheng W, Xiong Y, Otto E, Tang CA, Hua R, Verma R, Mori H, Zhang Y, Hu CA, Liu M, Garg P, Hodgin JB, Sun S, Bitzer M, Qi L. Yoshida S, et al. Among authors: hu ca. J Clin Invest. 2021 Apr 1;131(7):e143988. doi: 10.1172/JCI143988. J Clin Invest. 2021. PMID: 33591954 Free PMC article.
STING regulates BCR signaling in normal and malignant B cells.
Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA. Tang CA, et al. Among authors: hu ca. Cell Mol Immunol. 2021 Apr;18(4):1016-1031. doi: 10.1038/s41423-020-00552-0. Epub 2020 Sep 30. Cell Mol Immunol. 2021. PMID: 32999453 Free PMC article.
Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer.
Tcyganov EN, Hanabuchi S, Hashimoto A, Campbell D, Kar G, Slidel TW, Cayatte C, Landry A, Pilataxi F, Hayes S, Dougherty B, Hicks KC, Mulgrew K, Tang CA, Hu CA, Guo W, Grivennikov S, Ali MA, Beltra JC, Wherry EJ, Nefedova Y, Gabrilovich DI. Tcyganov EN, et al. Among authors: hu ca. J Clin Invest. 2021 Aug 16;131(16):e145971. doi: 10.1172/JCI145971. J Clin Invest. 2021. PMID: 34228641 Free PMC article.
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L. Ji Y, et al. Among authors: hu ca. Nat Cell Biol. 2023 May;25(5):726-739. doi: 10.1038/s41556-023-01138-4. Epub 2023 May 4. Nat Cell Biol. 2023. PMID: 37142791 Free PMC article.
Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy.
Shao A, Xu Q, Spalek WT, Cain CF, Kang CW, Tang CA, Del Valle JR, Hu CA. Shao A, et al. Among authors: hu ca. Mol Cancer Ther. 2020 Dec;19(12):2432-2444. doi: 10.1158/1535-7163.MCT-20-0127. Epub 2020 Oct 13. Mol Cancer Ther. 2020. PMID: 33051362 Free PMC article.
126 results