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CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, Wouters K, van den Hove DLA, Berkes D, Ledesma MD, Verhaagen J, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: bieberich e. Alzheimers Res Ther. 2021 Feb 17;13(1):45. doi: 10.1186/s13195-021-00780-0. Alzheimers Res Ther. 2021. PMID: 33597019 Free PMC article.
Visualization of Ceramide-Associated Proteins in Ceramide-Rich Platforms Using a Cross-Linkable Ceramide Analog and Proximity Ligation Assays With Anti-ceramide Antibody.
Jiang X, Zhu Z, Qin H, Tripathi P, Zhong L, Elsherbini A, Karki S, Crivelli SM, Zhi W, Wang G, Spassieva SD, Bieberich E. Jiang X, et al. Among authors: bieberich e. Front Cell Dev Biol. 2019 Aug 16;7:166. doi: 10.3389/fcell.2019.00166. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31475148 Free PMC article.
Sphingolipids in Alzheimer's disease, how can we target them?
Crivelli SM, Giovagnoni C, Visseren L, Scheithauer AL, de Wit N, den Hoedt S, Losen M, Mulder MT, Walter J, de Vries HE, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: bieberich e. Adv Drug Deliv Rev. 2020;159:214-231. doi: 10.1016/j.addr.2019.12.003. Epub 2020 Jan 3. Adv Drug Deliv Rev. 2020. PMID: 31911096 Review.
Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity.
Elsherbini A, Kirov AS, Dinkins MB, Wang G, Qin H, Zhu Z, Tripathi P, Crivelli SM, Bieberich E. Elsherbini A, et al. Among authors: bieberich e. Acta Neuropathol Commun. 2020 Apr 28;8(1):60. doi: 10.1186/s40478-020-00931-8. Acta Neuropathol Commun. 2020. PMID: 32345374 Free PMC article.
In vivo evidence of exosome-mediated Aβ neurotoxicity.
Elsherbini A, Qin H, Zhu Z, Tripathi P, Crivelli SM, Bieberich E. Elsherbini A, et al. Among authors: bieberich e. Acta Neuropathol Commun. 2020 Jul 6;8(1):100. doi: 10.1186/s40478-020-00981-y. Acta Neuropathol Commun. 2020. PMID: 32631455 Free PMC article. No abstract available.
118 results