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CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, Wouters K, van den Hove DLA, Berkes D, Ledesma MD, Verhaagen J, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: mielke mm. Alzheimers Res Ther. 2021 Feb 17;13(1):45. doi: 10.1186/s13195-021-00780-0. Alzheimers Res Ther. 2021. PMID: 33597019 Free PMC article.
Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration.
Jack CR Jr, Wiste HJ, Knopman DS, Vemuri P, Mielke MM, Weigand SD, Senjem ML, Gunter JL, Lowe V, Gregg BE, Pankratz VS, Petersen RC. Jack CR Jr, et al. Among authors: mielke mm. Neurology. 2014 May 6;82(18):1605-12. doi: 10.1212/WNL.0000000000000386. Epub 2014 Apr 4. Neurology. 2014. PMID: 24706010 Free PMC article.
Sphingolipids in Alzheimer's Disease and Related Disorders.
Martinez Martinez P, Mielke MM. Martinez Martinez P, et al. Among authors: mielke mm. J Alzheimers Dis. 2017;60(3):753-756. doi: 10.3233/JAD-170735. J Alzheimers Dis. 2017. PMID: 28922162 No abstract available.
Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods.
van Kruining D, Luo Q, van Echten-Deckert G, Mielke MM, Bowman A, Ellis S, Oliveira TG, Martinez-Martinez P. van Kruining D, et al. Among authors: mielke mm. Adv Drug Deliv Rev. 2020;159:232-244. doi: 10.1016/j.addr.2020.04.009. Epub 2020 Apr 28. Adv Drug Deliv Rev. 2020. PMID: 32360155 Free PMC article. Review.
522 results