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CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, Wouters K, van den Hove DLA, Berkes D, Ledesma MD, Verhaagen J, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: wouters k. Alzheimers Res Ther. 2021 Feb 17;13(1):45. doi: 10.1186/s13195-021-00780-0. Alzheimers Res Ther. 2021. PMID: 33597019 Free PMC article.
Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice.
Rombaut B, Schepers M, Tiane A, Mussen F, Koole L, Kessels S, Trippaers C, Jacobs R, Wouters K, Willems E, Veggel LV, Koulousakis P, Deluyker D, Bito V, Prickaerts J, Wens I, Brône B, van den Hove DLA, Vanmierlo T. Rombaut B, et al. Among authors: wouters k. Cells. 2024 Jun 8;13(12):1000. doi: 10.3390/cells13121000. Cells. 2024. PMID: 38920631 Free PMC article.
Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?".
Plat J, Baumgartner S, Vanmierlo T, Lütjohann D, Calkins KL, Burrin DG, Guthrie G, Thijs C, Te Velde AA, Vreugdenhil ACE, Sverdlov R, Garssen J, Wouters K, Trautwein EA, Wolfs TG, van Gorp C, Mulder MT, Riksen NP, Groen AK, Mensink RP. Plat J, et al. Among authors: wouters k. Prog Lipid Res. 2019 Apr;74:87-102. doi: 10.1016/j.plipres.2019.02.003. Epub 2019 Feb 26. Prog Lipid Res. 2019. PMID: 30822462 Free article. Review.
A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet.
Sari G, Meester EJ, van der Zee LC, Wouters K, van Lennep JR, Peppelenbosch M, Boonstra A, Van der Heiden K, Mulder MMT, Vanwolleghem T. Sari G, et al. Among authors: wouters k. Biochem Biophys Res Commun. 2020 Apr 2;524(2):510-515. doi: 10.1016/j.bbrc.2020.01.067. Epub 2020 Feb 1. Biochem Biophys Res Commun. 2020. PMID: 32014257 Free article.
Adipose tissue macrophages do not affect atherosclerosis development in mice.
Bijnen M, van de Gaar J, Vroomen M, Gijbels MJ, de Winther M, Schalkwijk CG, Wouters K. Bijnen M, et al. Among authors: wouters k. Atherosclerosis. 2019 Feb;281:31-37. doi: 10.1016/j.atherosclerosis.2018.12.010. Epub 2018 Dec 19. Atherosclerosis. 2019. PMID: 30654169 Free article.
322 results