Lu X - Search Results

1

Discovery of a Positron Emission Tomography Radiotracer Selectively Targeting the BD1 Bromodomains of BET Proteins.

Bai P, Lu X, Liu Y, Lan Y, Wang H, Fiedler S, Striar R, Wang C. Bai P, et al. Among authors: lu x. ACS Med Chem Lett. 2021 Jan 8;12(2):282-287. doi: 10.1021/acsmedchemlett.0c00650. eCollection 2021 Feb 11. ACS Med Chem Lett. 2021. PMID: 33603976 Free PMC article.

2

Design, synthesis, insecticidal activity and molecular docking of doramectin derivatives.

Zhang Q, Bai P, Zheng C, Cheng Y, Wang T, Lu X. Zhang Q, et al. Among authors: lu x. Bioorg Med Chem. 2019 Jun 15;27(12):2387-2396. doi: 10.1016/j.bmc.2018.12.040. Epub 2018 Dec 31. Bioorg Med Chem. 2019. PMID: 30626556

3

Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.

Bai P, Wang K, Zhang P, Shi J, Cheng X, Zhang Q, Zheng C, Cheng Y, Yang J, Lu X, Sang Z. Bai P, et al. Among authors: lu x. Eur J Med Chem. 2019 Dec 1;183:111737. doi: 10.1016/j.ejmech.2019.111737. Epub 2019 Sep 27. Eur J Med Chem. 2019. PMID: 31581002

4

Positron emission tomography probes targeting bromodomain and extra-terminal (BET) domains to enable in vivo neuroepigenetic imaging.

Bai P, Wey HY, Patnaik D, Lu X, Lan Y, Rokka J, Stephanie F, Haggarty SJ, Wang C. Bai P, et al. Among authors: lu x. Chem Commun (Camb). 2019 Oct 24;55(86):12932-12935. doi: 10.1039/c9cc06734e. Chem Commun (Camb). 2019. PMID: 31599282

5

A New Positron Emission Tomography Probe for Orexin Receptors Neuroimaging.

Bai P, Bai S, Placzek MS, Lu X, Fiedler SA, Ntaganda B, Wey HY, Wang C. Bai P, et al. Among authors: lu x. Molecules. 2020 Feb 25;25(5):1018. doi: 10.3390/molecules25051018. Molecules. 2020. PMID: 32106419 Free PMC article.

6

Radiosynthesis and in vivo evaluation of a new positron emission tomography radiotracer targeting bromodomain and extra-terminal domain (BET) family proteins.

Bai P, Lu X, Lan Y, Chen Z, Patnaik D, Fiedler S, Striar R, Haggarty SJ, Wang C. Bai P, et al. Among authors: lu x. Nucl Med Biol. 2020 May-Jun;84-85:96-101. doi: 10.1016/j.nucmedbio.2020.04.003. Epub 2020 Apr 9. Nucl Med Biol. 2020. PMID: 32320910

7

Design, Synthesis, and Insecticidal Activity of Novel Doramectin Derivatives Containing Acylurea and Acylthiourea Based on Hydrogen Bonding.

Zhang Q, Cheng Y, Zheng C, Bai P, Yang J, Lu X. Zhang Q, et al. Among authors: lu x. J Agric Food Chem. 2020 May 27;68(21):5806-5815. doi: 10.1021/acs.jafc.0c00230. Epub 2020 May 13. J Agric Food Chem. 2020. PMID: 32356977

8

Development of a Novel Positron Emission Tomography (PET) Radiotracer Targeting Bromodomain and Extra-Terminal Domain (BET) Family Proteins.

Bai P, Lan Y, Wang H, Chen Z, Fiedler S, Striar R, Lu X, Wang C. Bai P, et al. Among authors: lu x. Front Mol Biosci. 2020 Aug 12;7:198. doi: 10.3389/fmolb.2020.00198. eCollection 2020. Front Mol Biosci. 2020. PMID: 32903367 Free PMC article.

9

Design, Synthesis, and Antitumor Activity Evaluation of 2-Phenylthiazole-5-Carboxylic Acid Derivatives Targeting Transactivation Response RNA-Binding Protein 2.

Shi H, Yu J, Li L, Ji M, Li R, Peng T, Cheng Y, Wang T, Yang L, Wu Z, Zhang G, Wang F, Lu X. Shi H, et al. Among authors: lu x. J Med Chem. 2025 Jan 9;68(1):421-447. doi: 10.1021/acs.jmedchem.4c02041. Epub 2024 Dec 26. J Med Chem. 2025. PMID: 39722648

10

Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.

Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F. Peng T, et al. Among authors: lu x. J Med Chem. 2022 Aug 25;65(16):11010-11033. doi: 10.1021/acs.jmedchem.2c00189. Epub 2022 Jun 13. J Med Chem. 2022. PMID: 35695407

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