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Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms.
Brain Commun. 2021 Jan 5;3(1):fcaa231. doi: 10.1093/braincomms/fcaa231. eCollection 2021.
Brain Commun. 2021.
PMID: 33604571
Free PMC article.
Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease Model.
Landles C, Milton RE, Ali N, Flomen R, Flower M, Schindler F, Gomez-Paredes C, Bondulich MK, Osborne GF, Goodwin D, Salsbury G, Benn CL, Sathasivam K, Smith EJ, Tabrizi SJ, Wanker EE, Bates GP.
Landles C, et al. Among authors: milton re.
Brain Commun. 2020 Aug 3;2(2):fcaa066. doi: 10.1093/braincomms/fcaa066. eCollection 2020.
Brain Commun. 2020.
PMID: 32954323
Free PMC article.
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Alternative processing of human HTT mRNA with implications for Huntington's disease therapeutics.
Fienko S, Landles C, Sathasivam K, McAteer SJ, Milton RE, Osborne GF, Smith EJ, Jones ST, Bondulich MK, Danby ECE, Phillips J, Taxy BA, Kordasiewicz HB, Bates GP.
Fienko S, et al. Among authors: milton re.
Brain. 2022 Dec 19;145(12):4409-4424. doi: 10.1093/brain/awac241.
Brain. 2022.
PMID: 35793238
Free PMC article.
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Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
Smith EJ, Sathasivam K, Landles C, Osborne GF, Mason MA, Gomez-Paredes C, Taxy BA, Milton RE, Ast A, Schindler F, Zhang C, Duan W, Wanker EE, Bates GP.
Smith EJ, et al. Among authors: milton re.
Brain Commun. 2023 Jan 20;5(1):fcad010. doi: 10.1093/braincomms/fcad010. eCollection 2023.
Brain Commun. 2023.
PMID: 36756307
Free PMC article.
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