A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis.
Xu X, Denic A, Jordan LR, Wittenberg NJ, Warrington AE, Wootla B, Papke LM, Zoecklein LJ, Yoo D, Shaver J, Oh SH, Pease LR, Rodriguez M.
Xu X, et al. Among authors: yoo d.
Dis Model Mech. 2015 Aug 1;8(8):831-42. doi: 10.1242/dmm.020727. Epub 2015 May 28.
Dis Model Mech. 2015.
PMID: 26035393
Free PMC article.