Murillas R - Search Results

1

Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing.

Bonafont J, Mencía A, Chacón-Solano E, Srifa W, Vaidyanathan S, Romano R, Garcia M, Hervás-Salcedo R, Ugalde L, Duarte B, Porteus MH, Del Rio M, Larcher F, Murillas R. Bonafont J, et al. Among authors: murillas r. Mol Ther. 2021 Jun 2;29(6):2008-2018. doi: 10.1016/j.ymthe.2021.02.019. Epub 2021 Feb 18. Mol Ther. 2021. PMID: 33609734 Free PMC article.

2

Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.

Murillas R, Larcher F, Conti CJ, Santos M, Ullrich A, Jorcano JL. Murillas R, et al. EMBO J. 1995 Nov 1;14(21):5216-23. doi: 10.1002/j.1460-2075.1995.tb00206.x. EMBO J. 1995. PMID: 7489711 Free PMC article.

3

Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.

Larcher F, Robles AI, Duran H, Murillas R, Quintanilla M, Cano A, Conti CJ, Jorcano JL. Larcher F, et al. Among authors: murillas r. Cancer Res. 1996 Dec 1;56(23):5391-6. Cancer Res. 1996. PMID: 8968091

4

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development.

Larcher F, Murillas R, Bolontrade M, Conti CJ, Jorcano JL. Larcher F, et al. Among authors: murillas r. Oncogene. 1998 Jul 23;17(3):303-11. doi: 10.1038/sj.onc.1201928. Oncogene. 1998. PMID: 9690512

5

A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.

Casanova ML, Larcher F, Casanova B, Murillas R, Fernández-Aceñero MJ, Villanueva C, Martínez-Palacio J, Ullrich A, Conti CJ, Jorcano JL. Casanova ML, et al. Among authors: murillas r. Cancer Res. 2002 Jun 15;62(12):3402-7. Cancer Res. 2002. PMID: 12067982

6

Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.

Larcher F, Dellambra E, Rico L, Bondanza S, Murillas R, Cattoglio C, Mavilio F, Jorcano JL, Zambruno G, Del Rio M. Larcher F, et al. Among authors: murillas r. Mol Ther. 2007 Sep;15(9):1670-6. doi: 10.1038/sj.mt.6300238. Epub 2007 Jun 19. Mol Ther. 2007. PMID: 17579576 Free article.

7

Development of a bioengineered skin-humanized mouse model for psoriasis: dissecting epidermal-lymphocyte interacting pathways.

Guerrero-Aspizua S, García M, Murillas R, Retamosa L, Illera N, Duarte B, Holguín A, Puig S, Hernández MI, Meana A, Jorcano JL, Larcher F, Carretero M, Del Río M. Guerrero-Aspizua S, et al. Among authors: murillas r. Am J Pathol. 2010 Dec;177(6):3112-24. doi: 10.2353/ajpath.2010.100078. Epub 2010 Oct 22. Am J Pathol. 2010. PMID: 20971736 Free PMC article.

8

Risk assessment in skin gene therapy: viral-cellular fusion transcripts generated by proviral transcriptional read-through in keratinocytes transduced with self-inactivating lentiviral vectors.

Almarza D, Bussadori G, Navarro M, Mavilio F, Larcher F, Murillas R. Almarza D, et al. Among authors: murillas r. Gene Ther. 2011 Jul;18(7):674-81. doi: 10.1038/gt.2011.12. Epub 2011 Mar 3. Gene Ther. 2011. PMID: 21368897

9

Keratinocyte cell lines derived from severe generalized recessive epidermolysis bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo.

Chamorro C, Almarza D, Duarte B, Llames SG, Murillas R, García M, Cigudosa JC, Espinosa-Hevia L, Escámez MJ, Mencía A, Meana A, García-Escudero R, Moro R, Conti CJ, Del Río M, Larcher F. Chamorro C, et al. Among authors: murillas r. Exp Dermatol. 2013 Sep;22(9):601-3. doi: 10.1111/exd.12203. Exp Dermatol. 2013. PMID: 23947675

10

Long-term skin regeneration from a gene-targeted human epidermal stem cell clone.

Duarte B, Miselli F, Murillas R, Espinosa-Hevia L, Cigudosa JC, Recchia A, Del Río M, Larcher F. Duarte B, et al. Among authors: murillas r. Mol Ther. 2014 Nov;22(11):1878-80. doi: 10.1038/mt.2014.187. Mol Ther. 2014. PMID: 25365983 Free PMC article. No abstract available.

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