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Page 1
Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization.
Turner HL, Andrabi R, Cottrell CA, Richey ST, Song G, Callaghan S, Anzanello F, Moyer TJ, Abraham W, Melo M, Silva M, Scaringi N, Rakasz EG, Sattentau Q, Irvine DJ, Burton DR, Ward AB. Turner HL, et al. Among authors: irvine dj. bioRxiv [Preprint]. 2021 Feb 17:2021.02.16.431310. doi: 10.1101/2021.02.16.431310. bioRxiv. 2021. Update in: Sci Adv. 2021 Jul 28;7(31):eabh2791. doi: 10.1126/sciadv.abh2791. PMID: 33619491 Free PMC article. Updated. Preprint.
Biomaterials-Mediated Engineering of the Immune System.
Backlund C, Jalili-Firoozinezhad S, Kim B, Irvine DJ. Backlund C, et al. Among authors: irvine dj. Annu Rev Immunol. 2023 Apr 26;41:153-179. doi: 10.1146/annurev-immunol-101721-040259. Epub 2023 Jan 25. Annu Rev Immunol. 2023. PMID: 36696570 Free PMC article. Review.
Beyond antigens and adjuvants: formulating future vaccines.
Moyer TJ, Zmolek AC, Irvine DJ. Moyer TJ, et al. Among authors: irvine dj. J Clin Invest. 2016 Mar 1;126(3):799-808. doi: 10.1172/JCI81083. Epub 2016 Mar 1. J Clin Invest. 2016. PMID: 26928033 Free PMC article. Review.
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, Menis S, Georgeson E, Kubitz M, Adachi Y, Jones M, Mutafyan AA, Yun DS, Mayer CT, Ward AB, Burton DR, Wilson IA, Irvine DJ, Nussenzweig MC, Schief WR. Steichen JM, et al. Among authors: irvine dj. Immunity. 2016 Sep 20;45(3):483-496. doi: 10.1016/j.immuni.2016.08.016. Epub 2016 Sep 8. Immunity. 2016. PMID: 27617678 Free PMC article.
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, McCoy LE, Oom AL, Ozorowski G, Post KW, Sharma SK, Steichen JM, de Taeye SW, Tokatlian T, Torrents de la Peña A, Butera ST, LaBranche CC, Montefiori DC, Silvestri G, Wilson IA, Irvine DJ, Sanders RW, Schief WR, Ward AB, Wyatt RT, Barouch DH, Crotty S, Burton DR. Pauthner M, et al. Among authors: irvine dj. Immunity. 2017 Jun 20;46(6):1073-1088.e6. doi: 10.1016/j.immuni.2017.05.007. Immunity. 2017. PMID: 28636956 Free PMC article.
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S. Cirelli KM, et al. Among authors: irvine dj. Cell. 2019 May 16;177(5):1153-1171.e28. doi: 10.1016/j.cell.2019.04.012. Epub 2019 May 9. Cell. 2019. PMID: 31080066 Free PMC article.
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S. Cirelli KM, et al. Among authors: irvine dj. Cell. 2020 Jan 9;180(1):206. doi: 10.1016/j.cell.2019.12.027. Cell. 2020. PMID: 31923396 Free PMC article. No abstract available.
Engineered immunogen binding to alum adjuvant enhances humoral immunity.
Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, Agarwal Y, Li N, Burton DR, Ward AB, Schief WR, Crotty S, Irvine DJ. Moyer TJ, et al. Among authors: irvine dj. Nat Med. 2020 Mar;26(3):430-440. doi: 10.1038/s41591-020-0753-3. Epub 2020 Feb 17. Nat Med. 2020. PMID: 32066977 Free PMC article.
325 results