Dunn I - Search Results

1

The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes.

Klein KR, Freeman JLR, Dunn I, Dvergsten C, Kirkman MS, Buse JB, Valcarce C; SimpliciT1 research group. Klein KR, et al. Among authors: dunn i. Diabetes Care. 2021 Apr;44(4):960-968. doi: 10.2337/dc20-2684. Epub 2021 Feb 23. Diabetes Care. 2021. PMID: 33622669 Free PMC article. Clinical Trial.

2

Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator.

Vella A, Freeman JLR, Dunn I, Keller K, Buse JB, Valcarce C. Vella A, et al. Among authors: dunn i. Sci Transl Med. 2019 Jan 16;11(475):eaau3441. doi: 10.1126/scitranslmed.aau3441. Sci Transl Med. 2019. PMID: 30651321 Clinical Trial.

3

Impact of the hepatoselective glucokinase activator TTP399 on ketoacidosis during insulin withdrawal in people with type 1 diabetes.

Klein KR, Boeder SC, Freeman JLR, Dunn I, Dvergsten C, Madduri S, Giovannetti ER, Valcarce C, Buse JB, Pettus JH. Klein KR, et al. Among authors: dunn i. Diabetes Obes Metab. 2022 Aug;24(8):1439-1447. doi: 10.1111/dom.14697. Epub 2022 Jun 4. Diabetes Obes Metab. 2022. PMID: 35661378 Free PMC article. Clinical Trial.

4

Development of Azeliragon, an Oral Small Molecule Antagonist of the Receptor for Advanced Glycation Endproducts, for the Potential Slowing of Loss of Cognition in Mild Alzheimer's Disease.

Burstein AH, Sabbagh M, Andrews R, Valcarce C, Dunn I, Altstiel L. Burstein AH, et al. Among authors: dunn i. J Prev Alzheimers Dis. 2018;5(2):149-154. doi: 10.14283/jpad.2018.18. J Prev Alzheimers Dis. 2018. PMID: 29616709 Review.

5

Assessment of Azeliragon QTc Liability Through Integrated, Model-Based Concentration QTc Analysis.

Burstein AH, Brantley SJ, Dunn I, Altstiel LD, Schmith V. Burstein AH, et al. Among authors: dunn i. Clin Pharmacol Drug Dev. 2019 May;8(4):426-435. doi: 10.1002/cpdd.689. Epub 2019 Apr 1. Clin Pharmacol Drug Dev. 2019. PMID: 30934161

6

Extended Risk-Based Monitoring Model, On-Demand Query-Driven Source Data Verification, and Their Economic Impact on Clinical Trial Operations.

Tantsyura V, Dunn IM, Waters J, Fendt K, Kim YJ, Viola D, Mitchel J. Tantsyura V, et al. Ther Innov Regul Sci. 2016 Jan;50(1):115-122. doi: 10.1177/2168479015596020. Ther Innov Regul Sci. 2016. PMID: 30236023

7

Risk-Based Monitoring: A Closer Statistical Look at Source Document Verification, Queries, Study Size Effects, and Data Quality.

Tantsyura V, Dunn IM, Fendt K, Kim YJ, Waters J, Mitchel J. Tantsyura V, et al. Ther Innov Regul Sci. 2015 Nov;49(6):903-910. doi: 10.1177/2168479015586001. Ther Innov Regul Sci. 2015. PMID: 30222374

8

Efficacy of videoconferencing-delivered cognitive behavioural therapy to reduce anxiety disorder severity in LGBTQ+ people: An exploratory trial protocol.

Dunn IBJMD, Power E, Casey LJ, Wootton BM. Dunn IBJMD, et al. PLoS One. 2025 Jan 24;20(1):e0316857. doi: 10.1371/journal.pone.0316857. eCollection 2025. PLoS One. 2025. PMID: 39854414 Clinical Trial.

9

Benchmarking the Efficacy of Salvage Systemic Therapies for Recurrent Meningioma: A RANO Group Systematic Review and Meta-analysis to Guide Clinical Trial Design.

Kotecha R, Akdemir EY, Kutuk T, Ilgin C, Ahluwalia MS, Bi WL, Blakeley J, Dixit KS, Dunn IF, Galanis E, Galldiks N, Huang RY, Johnson DR, Kaley TJ, Kamson DO, Kurz SC, McDermott MW, Odia Y, Preusser M, Raizer J, Reardon DA, Rogers CL, Ruda R, Schiff D, Vogelbaum MA, Weller M, Wen PY, Mehta MP. Kotecha R, et al. Among authors: dunn if. Neuro Oncol. 2025 Jan 14:noaf009. doi: 10.1093/neuonc/noaf009. Online ahead of print. Neuro Oncol. 2025. PMID: 39807850

10

Adult Cerebellopontine Angle Medulloblastoma: A Systematic Review of Clinical Features, Management Approaches, and Patient Outcomes.

Balasubramanian K, Kharbat AF, Call-Orellana F, Tavakol SA, Fassina GR, Janssen C, Bin Alamer O, Zuccato JA, Dunn IF. Balasubramanian K, et al. Among authors: dunn if. Cancers (Basel). 2024 Dec 20;16(24):4242. doi: 10.3390/cancers16244242. Cancers (Basel). 2024. PMID: 39766141 Free PMC article. Review.

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