Irani S - Search Results

1

The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration.

Zhou R, Wu Q, Wang M, Irani S, Li X, Zhang Q, Meng F, Liu S, Zhang F, Wu L, Lin X, Wang X, Zou J, Song H, Qin J, Liang T, Feng XH, Zhang YJ, Xu P. Zhou R, et al. Among authors: irani s. PLoS Biol. 2021 Feb 25;19(2):e3001122. doi: 10.1371/journal.pbio.3001122. eCollection 2021 Feb. PLoS Biol. 2021. PMID: 33630828 Free PMC article.

2

Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages.

Li W, Irani S, Crutchfield A, Hodge K, Matthews W, Patel P, Zhang YJ, Stone E. Li W, et al. Among authors: irani s. Biochemistry. 2016 Feb 16;55(6):960-9. doi: 10.1021/acs.biochem.5b01157. Epub 2016 Feb 2. Biochemistry. 2016. PMID: 26780688 Free PMC article.

3

Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.

Irani S, Yogesha SD, Mayfield J, Zhang M, Zhang Y, Matthews WL, Nie G, Prescott NA, Zhang YJ. Irani S, et al. Sci Signal. 2016 Mar 1;9(417):ra24. doi: 10.1126/scisignal.aad4805. Sci Signal. 2016. PMID: 26933063 Free PMC article.

4

Chemical Tools for Studying the Impact of cis/trans Prolyl Isomerization on Signaling: A Case Study on RNA Polymerase II Phosphatase Activity and Specificity.

Burkholder NT, Medellin B, Irani S, Matthews W, Showalter SA, Zhang YJ. Burkholder NT, et al. Among authors: irani s. Methods Enzymol. 2018;607:269-297. doi: 10.1016/bs.mie.2018.04.020. Epub 2018 Jun 23. Methods Enzymol. 2018. PMID: 30149861 Free PMC article.

5

Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).

Burkholder NT, Mayfield JE, Yu X, Irani S, Arce DK, Jiang F, Matthews WL, Xue Y, Zhang YJ. Burkholder NT, et al. Among authors: irani s. J Biol Chem. 2018 Oct 26;293(43):16851-16861. doi: 10.1074/jbc.RA118.004722. Epub 2018 Sep 14. J Biol Chem. 2018. PMID: 30217818 Free PMC article.

6

Crystal Structure of the Ergothioneine Sulfoxide Synthase from Candidatus Chloracidobacterium thermophilum and Structure-Guided Engineering To Modulate Its Substrate Selectivity.

Naowarojna N, Irani S, Hu W, Cheng R, Zhang L, Li X, Chen J, Zhang YJ, Liu P. Naowarojna N, et al. Among authors: irani s. ACS Catal. 2019 Aug 2;9(8):6955-6961. doi: 10.1021/acscatal.9b02054. Epub 2019 Jul 2. ACS Catal. 2019. PMID: 32257583 Free PMC article.

7

Electrophoretic Mobility Shift Assay of in vitro Phosphorylated RNA Polymerase II Carboxyl-terminal Domain Substrates.

Mayfield JE, Irani S, Zhang Y. Mayfield JE, et al. Among authors: irani s. Bio Protoc. 2020 Jun 20;10(12):e3648. doi: 10.21769/BioProtoc.3648. eCollection 2020 Jun 20. Bio Protoc. 2020. PMID: 33659319 Free PMC article.

8

Simplicity is the Ultimate Sophistication-Crosstalk of Post-translational Modifications on the RNA Polymerase II.

Venkat Ramani MK, Yang W, Irani S, Zhang Y. Venkat Ramani MK, et al. Among authors: irani s. J Mol Biol. 2021 Jul 9;433(14):166912. doi: 10.1016/j.jmb.2021.166912. Epub 2021 Mar 5. J Mol Biol. 2021. PMID: 33676925 Free PMC article. Review.

9

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia.

Polyanskaya SA, Moreno RY, Lu B, Feng R, Yao Y, Irani S, Klingbeil O, Yang Z, Wei Y, Demerdash OE, Benjamin LA, Weiss MJ, Zhang YJ, Vakoc CR. Polyanskaya SA, et al. Among authors: irani s. Cell Rep. 2022 Jan 11;38(2):110233. doi: 10.1016/j.celrep.2021.110233. Cell Rep. 2022. PMID: 35021089 Free PMC article.

10

Thr⁴ phosphorylation on RNA Pol II occurs at early transcription regulating 3'-end processing.

Moreno RY, Panina SB, Irani S, Hardtke HA, Stephenson R, Floyd BM, Marcotte EM, Zhang Q, Zhang YJ. Moreno RY, et al. Among authors: irani s. Sci Adv. 2024 Sep 6;10(36):eadq0350. doi: 10.1126/sciadv.adq0350. Epub 2024 Sep 6. Sci Adv. 2024. PMID: 39241064 Free PMC article.

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