Kawai S - Search Results

1

Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias.

Pretemer Y, Kawai S, Nagata S, Nishio M, Watanabe M, Tamaki S, Alev C, Yamanaka Y, Xue JY, Wang Z, Fukiage K, Tsukanaka M, Futami T, Ikegawa S, Toguchida J. Pretemer Y, et al. Among authors: kawai s. Stem Cell Reports. 2021 Mar 9;16(3):610-625. doi: 10.1016/j.stemcr.2021.01.014. Epub 2021 Feb 25. Stem Cell Reports. 2021. PMID: 33636111 Free PMC article.

2

Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis.

Otomo N, Takeda K, Kawai S, Kou I, Guo L, Osawa M, Alev C, Kawakami N, Miyake N, Matsumoto N, Yasuhiko Y, Kotani T, Suzuki T, Uno K, Sudo H, Inami S, Taneichi H, Shigematsu H, Watanabe K, Yonezawa I, Sugawara R, Taniguchi Y, Minami S, Kaneko K, Nakamura M, Matsumoto M, Toguchida J, Watanabe K, Ikegawa S. Otomo N, et al. Among authors: kawai s. J Med Genet. 2019 Sep;56(9):622-628. doi: 10.1136/jmedgenet-2018-105920. Epub 2019 Apr 22. J Med Genet. 2019. PMID: 31015262

3

In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes.

Kawai S, Yoshitomi H, Sunaga J, Alev C, Nagata S, Nishio M, Hada M, Koyama Y, Uemura M, Sekiguchi K, Maekawa H, Ikeya M, Tamaki S, Jin Y, Harada Y, Fukiage K, Adachi T, Matsuda S, Toguchida J. Kawai S, et al. Nat Biomed Eng. 2019 Jul;3(7):558-570. doi: 10.1038/s41551-019-0410-7. Epub 2019 Jun 10. Nat Biomed Eng. 2019. PMID: 31182836

4

Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1.

Maekawa H, Kawai S, Nishio M, Nagata S, Jin Y, Yoshitomi H, Matsuda S, Toguchida J. Maekawa H, et al. Among authors: kawai s. Orphanet J Rare Dis. 2020 May 24;15(1):122. doi: 10.1186/s13023-020-01406-8. Orphanet J Rare Dis. 2020. PMID: 32448372 Free PMC article.

5

Induction and expansion of human PRRX1⁺ limb-bud-like mesenchymal cells from pluripotent stem cells.

Yamada D, Nakamura M, Takao T, Takihira S, Yoshida A, Kawai S, Miura A, Ming L, Yoshitomi H, Gozu M, Okamoto K, Hojo H, Kusaka N, Iwai R, Nakata E, Ozaki T, Toguchida J, Takarada T. Yamada D, et al. Among authors: kawai s. Nat Biomed Eng. 2021 Aug;5(8):926-940. doi: 10.1038/s41551-021-00778-x. Epub 2021 Aug 9. Nat Biomed Eng. 2021. PMID: 34373601

6

Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.

Maekawa H, Jin Y, Nishio M, Kawai S, Nagata S, Kamakura T, Yoshitomi H, Niwa A, Saito MK, Matsuda S, Toguchida J. Maekawa H, et al. Among authors: kawai s. Orphanet J Rare Dis. 2022 Sep 21;17(1):364. doi: 10.1186/s13023-022-02506-3. Orphanet J Rare Dis. 2022. PMID: 36131296 Free PMC article.

7

3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes.

Kawai S, Sunaga J, Nagata S, Nishio M, Fukuda M, Kamakura T, Sun L, Jin Y, Sakamoto S, Watanabe A, Matsuda S, Adachi T, Toguchida J. Kawai S, et al. Sci Rep. 2023 Jan 19;13(1):1094. doi: 10.1038/s41598-023-27556-w. Sci Rep. 2023. PMID: 36658197 Free PMC article.

8

Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC-Derived Chondrocytes.

Kamakura T, Jin Y, Nishio M, Nagata S, Fukuda M, Sun L, Kawai S, Toguchida J. Kamakura T, et al. Among authors: kawai s. JBMR Plus. 2023 Mar 29;7(5):e10737. doi: 10.1002/jbm4.10737. eCollection 2023 May. JBMR Plus. 2023. PMID: 37197316 Free PMC article.

9

Automated cell culture system for the production of cell aggregates with growth plate-like structure from induced pluripotent stem cells.

Ohta A, Kawai S, Pretemer Y, Nishio M, Nagata S, Fuse H, Yamagishi Y, Toguchida J. Ohta A, et al. Among authors: kawai s. SLAS Technol. 2023 Dec;28(6):433-441. doi: 10.1016/j.slast.2023.08.002. Epub 2023 Aug 9. SLAS Technol. 2023. PMID: 37562511 Free article.

10

Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva.

Sun L, Jin Y, Nishio M, Watanabe M, Kamakura T, Nagata S, Fukuda M, Maekawa H, Kawai S, Yamamoto T, Toguchida J. Sun L, et al. Among authors: kawai s. Life Sci Alliance. 2024 Feb 16;7(5):e202302219. doi: 10.26508/lsa.202302219. Print 2024 May. Life Sci Alliance. 2024. PMID: 38365425 Free PMC article.

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