Dongola TH - Search Results

1

Auto QSAR-based active learning docking for hit identification of potential inhibitors of Plasmodium falciparum Hsp90 as antimalarial agents.

Matlhodi T, Makatsela LP, Dongola TH, Simelane MBC, Shonhai A, Gumede NJ, Mokoena F. Matlhodi T, et al. Among authors: dongola th. PLoS One. 2024 Nov 25;19(11):e0308969. doi: 10.1371/journal.pone.0308969. eCollection 2024. PLoS One. 2024. PMID: 39585817 Free PMC article.

2

Ursolic acid acetate and iso-mukaadial acetate bind to Plasmodium falciparum Hsp90, abrogating its chaperone function in vitro.

Nndwammbi AAT, Dongola TH, Shonhai A, Mokoena F, Pooe OJ, Simelane MBC. Nndwammbi AAT, et al. Among authors: dongola th. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jul;397(7):5179-5192. doi: 10.1007/s00210-024-02944-9. Epub 2024 Jan 22. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38252299 Free PMC article.

3

Insertion of GGMP repeat residues of Plasmodium falciparum Hsp70-1 in the lid of DnaK adversely impacts client recognition.

Dongola TH, Chakafana G, Middlemiss C, Mafethe O, Mokoena F, Zininga T, Shonhai A. Dongola TH, et al. Int J Biol Macromol. 2024 Jan;255:128070. doi: 10.1016/j.ijbiomac.2023.128070. Epub 2023 Nov 18. Int J Biol Macromol. 2024. PMID: 37981279

4

Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Plasmodium falciparum Hsp90.

Mafethe O, Ntseane T, Dongola TH, Shonhai A, Gumede NJ, Mokoena F. Mafethe O, et al. Among authors: dongola th. ACS Omega. 2023 Sep 26;8(41):38220-38232. doi: 10.1021/acsomega.3c04494. eCollection 2023 Oct 17. ACS Omega. 2023. PMID: 37867657 Free PMC article.

5

Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro.

Ramatsui L, Dongola TH, Zininga T, Multhoff G, Shonhai A. Ramatsui L, et al. Among authors: dongola th. Cell Stress Chaperones. 2023 May;28(3):321-331. doi: 10.1007/s12192-023-01339-8. Epub 2023 Apr 19. Cell Stress Chaperones. 2023. PMID: 37074531 Free PMC article.

6

Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide.

Muthelo T, Mulaudzi V, Netshishivhe M, Dongola TH, Kok M, Makumire S, de Villiers M, Burger A, Zininga T, Shonhai A. Muthelo T, et al. Among authors: dongola th. Front Mol Biosci. 2022 Sep 13;9:947203. doi: 10.3389/fmolb.2022.947203. eCollection 2022. Front Mol Biosci. 2022. PMID: 36177352 Free PMC article.

7

Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding.

Makumire S, Dongola TH, Chakafana G, Tshikonwane L, Chauke CT, Maharaj T, Zininga T, Shonhai A. Makumire S, et al. Among authors: dongola th. Int J Mol Sci. 2021 Feb 23;22(4):2226. doi: 10.3390/ijms22042226. Int J Mol Sci. 2021. PMID: 33672387 Free PMC article.

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