Surapaneni S - Search Results

1

Absorption, Metabolism, and Excretion, In Vitro Pharmacology, and Clinical Pharmacokinetics of Ozanimod, a Novel Sphingosine 1-Phosphate Receptor Modulator.

Surapaneni S, Yerramilli U, Bai A, Dalvie D, Brooks J, Wang X, Selkirk JV, Yan YG, Zhang P, Hargreaves R, Kumar G, Palmisano M, Tran JQ. Surapaneni S, et al. Drug Metab Dispos. 2021 May;49(5):405-419. doi: 10.1124/dmd.120.000220. Epub 2021 Mar 4. Drug Metab Dispos. 2021. PMID: 33674268 Clinical Trial.

2

Investigation into MAO B-Mediated Formation of CC112273, a Major Circulating Metabolite of Ozanimod, in Humans and Preclinical Species: Stereospecific Oxidative Deamination of (S)-Enantiomer of Indaneamine (RP101075) by MAO B.

Bai A, Shanmugasundaram V, Selkirk JV, Surapaneni S, Dalvie D. Bai A, et al. Among authors: surapaneni s. Drug Metab Dispos. 2021 Aug;49(8):601-609. doi: 10.1124/dmd.121.000447. Epub 2021 May 19. Drug Metab Dispos. 2021. PMID: 34011531

3

Absorption, distribution, metabolism, and excretion of mTOR kinase inhibitor CC-223 in rats, dogs, and humans.

Tong Z, Atsriku C, Yerramilli U, Wang X, Nissel J, Li Y, Surapaneni S. Tong Z, et al. Among authors: surapaneni s. Xenobiotica. 2019 Jan;49(1):43-53. doi: 10.1080/00498254.2017.1413718. Epub 2017 Dec 19. Xenobiotica. 2019. PMID: 29206565

4

Absorption, distribution, metabolism and excretion of an isocitrate dehydrogenase-2 inhibitor enasidenib in rats and humans.

Tong Z, Atsriku C, Yerramilli U, Wang X, Li Y, Reyes J, Fan B, Yang H, Hoffmann M, Surapaneni S. Tong Z, et al. Among authors: surapaneni s. Xenobiotica. 2019 Feb;49(2):200-210. doi: 10.1080/00498254.2018.1425511. Epub 2018 Jan 22. Xenobiotica. 2019. PMID: 29320949

5

Identification of a novel in vitro metabonate from liver microsomal incubations.

Li C, Surapaneni S, Zeng Q, Marquez B, Chow D, Kumar G. Li C, et al. Among authors: surapaneni s. Drug Metab Dispos. 2006 Jun;34(6):901-5. doi: 10.1124/dmd.105.008367. Epub 2006 Mar 22. Drug Metab Dispos. 2006. PMID: 16554371

6

In vitro metabolism of the novel, highly selective oral angiogenesis inhibitor motesanib diphosphate in preclinical species and in humans.

Li C, Kuchimanchi M, Hickman D, Poppe L, Hayashi M, Zhou Y, Subramanian R, Kumar G, Surapaneni S. Li C, et al. Among authors: surapaneni s. Drug Metab Dispos. 2009 Jul;37(7):1378-94. doi: 10.1124/dmd.108.025742. Epub 2009 Apr 16. Drug Metab Dispos. 2009. PMID: 19372226

7

Pharmacokinetics, metabolism and excretion of [(14)C]-lenalidomide following oral administration in healthy male subjects.

Chen N, Wen L, Lau H, Surapaneni S, Kumar G. Chen N, et al. Among authors: surapaneni s. Cancer Chemother Pharmacol. 2012 Mar;69(3):789-97. doi: 10.1007/s00280-011-1760-3. Epub 2011 Oct 29. Cancer Chemother Pharmacol. 2012. PMID: 22037879 Free PMC article. Clinical Trial.

8

In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism.

Atsriku C, Hoffmann M, Moghaddam M, Kumar G, Surapaneni S. Atsriku C, et al. Among authors: surapaneni s. Xenobiotica. 2015;45(6):465-80. doi: 10.3109/00498254.2014.991367. Epub 2014 Dec 5. Xenobiotica. 2015. PMID: 25475995

9

Metabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans.

Atsriku C, Hoffmann M, Ye Y, Kumar G, Surapaneni S. Atsriku C, et al. Among authors: surapaneni s. Xenobiotica. 2015 May;45(5):428-41. doi: 10.3109/00498254.2014.990949. Epub 2014 Dec 8. Xenobiotica. 2015. PMID: 25482583 Clinical Trial.

10

Application of a "Fit for Purpose" PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide.

Narayanan R, Hoffmann M, Kumar G, Surapaneni S. Narayanan R, et al. Among authors: surapaneni s. Drug Metab Lett. 2016;10(3):172-179. doi: 10.2174/1872312810666160729124745. Drug Metab Lett. 2016. PMID: 27604990

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