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Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro.
Unal MA, Bitirim CV, Summak GY, Bereketoglu S, Cevher Zeytin I, Besbinar O, Gurcan C, Aydos D, Goksoy E, Kocakaya E, Eran Z, Murat M, Demir N, Aksoy Ozer ZB, Somers J, Demir E, Nazir H, Ozkan SA, Ozkul A, Azap A, Yilmazer A, Akcali KC. Unal MA, et al. Among authors: bereketoglu s. Can J Physiol Pharmacol. 2021 May;99(5):449-460. doi: 10.1139/cjpp-2020-0734. Epub 2021 Mar 9. Can J Physiol Pharmacol. 2021. PMID: 33689451 Free article.