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Page 1
Prosaposin mediates inflammation in atherosclerosis.
van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Pérez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirski FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen NP, Mulder WJM, Duivenvoorden R. van Leent MMT, et al. Among authors: beldman tj. Sci Transl Med. 2021 Mar 10;13(584):eabe1433. doi: 10.1126/scitranslmed.abe1433. Sci Transl Med. 2021. PMID: 33692130 Free PMC article.
Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.
Beldman TJ, Senders ML, Alaarg A, Pérez-Medina C, Tang J, Zhao Y, Fay F, Deichmöller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E. Beldman TJ, et al. ACS Nano. 2017 Jun 27;11(6):5785-5799. doi: 10.1021/acsnano.7b01385. Epub 2017 May 15. ACS Nano. 2017. PMID: 28463501 Free PMC article.
Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy.
Beldman TJ, Malinova TS, Desclos E, Grootemaat AE, Misiak ALS, van der Velden S, van Roomen CPAA, Beckers L, van Veen HA, Krawczyk PM, Hoebe RA, Sluimer JC, Neele AE, de Winther MPJ, van der Wel NN, Lutgens E, Mulder WJM, Huveneers S, Kluza E. Beldman TJ, et al. ACS Nano. 2019 Dec 24;13(12):13759-13774. doi: 10.1021/acsnano.8b08875. Epub 2019 Jul 10. ACS Nano. 2019. PMID: 31268670 Free PMC article.
Diverse ultrastructural landscape of atherosclerotic endothelium.
Kluza E, Beldman TJ, Shami A, Scholl ER, Malinova TS, Grootemaat AE, van der Wel NN, Gonçalves I, Huveneers S, Mulder WJM, Lutgens E. Kluza E, et al. Among authors: beldman tj. Atherosclerosis. 2021 Dec;339:35-45. doi: 10.1016/j.atherosclerosis.2021.11.017. Epub 2021 Nov 19. Atherosclerosis. 2021. PMID: 34847419 Free article.
Self-gated, dynamic contrast-enhanced magnetic resonance imaging with compressed-sensing reconstruction for evaluating endothelial permeability in the aortic root of atherosclerotic mice.
Calcagno C, David JA, Motaal AG, Coolen BF, Beldman T, Corbin A, Kak A, Ramachandran S, Pruzan A, Sridhar A, Soler R, Faries CM, Fayad ZA, Mulder WJM, Strijkers GJ. Calcagno C, et al. NMR Biomed. 2023 Jan;36(1):e4823. doi: 10.1002/nbm.4823. Epub 2022 Sep 23. NMR Biomed. 2023. PMID: 36031706 Free PMC article.
Engineering cytokine therapeutics.
Deckers J, Anbergen T, Hokke AM, de Dreu A, Schrijver DP, de Bruin K, Toner YC, Beldman TJ, Spangler JB, de Greef TFA, Grisoni F, van der Meel R, Joosten LAB, Merkx M, Netea MG, Mulder WJM. Deckers J, et al. Among authors: beldman tj. Nat Rev Bioeng. 2023;1(4):286-303. doi: 10.1038/s44222-023-00030-y. Epub 2023 Feb 16. Nat Rev Bioeng. 2023. PMID: 37064653 Free PMC article. Review.
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
Schrijver DP, Röring RJ, Deckers J, de Dreu A, Toner YC, Prevot G, Priem B, Munitz J, Nugraha EG, van Elsas Y, Azzun A, Anbergen T, Groh LA, Becker AMD, Pérez-Medina C, Oosterwijk RS, Novakovic B, Moorlag SJCFM, Jansen A, Pickkers P, Kox M, Beldman TJ, Kluza E, van Leent MMT, Teunissen AJP, van der Meel R, Fayad ZA, Joosten LAB, Fisher EA, Merkx M, Netea MG, Mulder WJM. Schrijver DP, et al. Among authors: beldman tj. Nat Biomed Eng. 2023 Sep;7(9):1097-1112. doi: 10.1038/s41551-023-01050-0. Epub 2023 Jun 8. Nat Biomed Eng. 2023. PMID: 37291433 Free PMC article.
Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy.
Wauters AC, Scheerstra JF, van Leent MMT, Teunissen AJP, Priem B, Beldman TJ, Rother N, Duivenvoorden R, Prévot G, Munitz J, Toner YC, Deckers J, van Elsas Y, Mora-Raimundo P, Chen G, Nauta SA, Verschuur AVD, Griffioen AW, Schrijver DP, Anbergen T, Li Y, Wu H, Mason AF, van Stevendaal MHME, Kluza E, Post RAJ, Joosten LAB, Netea MG, Calcagno C, Fayad ZA, van der Meel R, Schroeder A, Abdelmohsen LKEA, Mulder WJM, van Hest JCM. Wauters AC, et al. Among authors: beldman tj. Nat Nanotechnol. 2024 Nov;19(11):1735-1744. doi: 10.1038/s41565-024-01727-w. Epub 2024 Jul 31. Nat Nanotechnol. 2024. PMID: 39085390 Free PMC article.
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
Koenis DS, Medzikovic L, Vos M, Beldman TJ, van Loenen PB, van Tiel CM, Hamers AAJ, Otermin Rubio I, de Waard V, de Vries CJM. Koenis DS, et al. Among authors: beldman tj. J Biol Chem. 2018 Sep 28;293(39):15070-15083. doi: 10.1074/jbc.RA118.002720. Epub 2018 Aug 15. J Biol Chem. 2018. PMID: 30111591 Free PMC article.