Nagai Y - Search Results

1

Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold.

Hervás R, Del Carmen Fernández-Ramírez M, Galera-Prat A, Suzuki M, Nagai Y, Bruix M, Menéndez M, Laurents DV, Carrión-Vázquez M. Hervás R, et al. Among authors: nagai y. BMC Biol. 2021 Mar 11;19(1):43. doi: 10.1186/s12915-021-00967-9. BMC Biol. 2021. PMID: 33706787 Free PMC article.

2

p62 plays a protective role in the autophagic degradation of polyglutamine protein oligomers in polyglutamine disease model flies.

Saitoh Y, Fujikake N, Okamoto Y, Popiel HA, Hatanaka Y, Ueyama M, Suzuki M, Gaumer S, Murata M, Wada K, Nagai Y. Saitoh Y, et al. Among authors: nagai y. J Biol Chem. 2015 Jan 16;290(3):1442-53. doi: 10.1074/jbc.M114.590281. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480790 Free PMC article.

3

Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.

Takeuchi T, Suzuki M, Fujikake N, Popiel HA, Kikuchi H, Futaki S, Wada K, Nagai Y. Takeuchi T, et al. Among authors: nagai y. Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2497-506. doi: 10.1073/pnas.1412651112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918398 Free PMC article.

4

Normalization of Overexpressed α-Synuclein Causing Parkinson's Disease By a Moderate Gene Silencing With RNA Interference.

Takahashi M, Suzuki M, Fukuoka M, Fujikake N, Watanabe S, Murata M, Wada K, Nagai Y, Hohjoh H. Takahashi M, et al. Among authors: nagai y. Mol Ther Nucleic Acids. 2015 May 12;4:e241. doi: 10.1038/mtna.2015.14. Mol Ther Nucleic Acids. 2015. PMID: 25965551 Free article.

5

Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease.

Suzuki M, Fujikake N, Takeuchi T, Kohyama-Koganeya A, Nakajima K, Hirabayashi Y, Wada K, Nagai Y. Suzuki M, et al. Among authors: nagai y. Hum Mol Genet. 2015 Dec 1;24(23):6675-86. doi: 10.1093/hmg/ddv372. Epub 2015 Sep 11. Hum Mol Genet. 2015. PMID: 26362253

6

Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation.

Hervás R, Li L, Majumdar A, Fernández-Ramírez Mdel C, Unruh JR, Slaughter BD, Galera-Prat A, Santana E, Suzuki M, Nagai Y, Bruix M, Casas-Tintó S, Menéndez M, Laurents DV, Si K, Carrión-Vázquez M. Hervás R, et al. Among authors: nagai y. PLoS Biol. 2016 Jan 26;14(1):e1002361. doi: 10.1371/journal.pbio.1002361. eCollection 2016 Jan. PLoS Biol. 2016. PMID: 26812143 Free PMC article.

7

Pathological role of lipid interaction with α-synuclein in Parkinson's disease.

Suzuki M, Sango K, Wada K, Nagai Y. Suzuki M, et al. Among authors: nagai y. Neurochem Int. 2018 Oct;119:97-106. doi: 10.1016/j.neuint.2017.12.014. Epub 2018 Jan 3. Neurochem Int. 2018. PMID: 29305919 Free article. Review.

8

Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.

Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y, Aoki M. Yoshida S, et al. Among authors: nagai y. Hum Mol Genet. 2018 Mar 1;27(5):823-836. doi: 10.1093/hmg/ddy003. Hum Mol Genet. 2018. PMID: 29309590

9

E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease.

Sakai R, Suzuki M, Ueyama M, Takeuchi T, Minakawa EN, Hayakawa H, Baba K, Mochizuki H, Nagai Y. Sakai R, et al. Among authors: nagai y. PLoS One. 2019 Jun 26;14(6):e0218261. doi: 10.1371/journal.pone.0218261. eCollection 2019. PLoS One. 2019. PMID: 31242217 Free PMC article.

10

Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson's Disease.

Ikenaka K, Suzuki M, Mochizuki H, Nagai Y. Ikenaka K, et al. Among authors: nagai y. Front Neurosci. 2019 Jul 3;13:693. doi: 10.3389/fnins.2019.00693. eCollection 2019. Front Neurosci. 2019. PMID: 31333408 Free PMC article. Review.

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