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Long QT Syndrome KCNH2 Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Feng L, Zhang J, Lee C, Kim G, Liu F, Petersen AJ, Lim E, Anderson CL, Orland KM, Robertson GA, Eckhardt LL, January CT, Kamp TJ. Feng L, et al. Among authors: january ct. Circ Arrhythm Electrophysiol. 2021 Apr;14(4):e009343. doi: 10.1161/CIRCEP.120.009343. Epub 2021 Mar 17. Circ Arrhythm Electrophysiol. 2021. PMID: 33729832 Free PMC article.
Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr).
Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Rajamani S, et al. Among authors: january ct. Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1278-88. doi: 10.1152/ajpheart.00777.2005. Epub 2005 Oct 14. Am J Physiol Heart Circ Physiol. 2006. PMID: 16227340 Free article.
Harry A. Fozzard, MD: 1931–2014.
Kamp TJ, January CT. Kamp TJ, et al. Among authors: january ct. Circ Res. 2015 Feb 13;116(4):552-3. doi: 10.1161/CIRCRESAHA.115.306038. Circ Res. 2015. PMID: 25821880 Free PMC article. No abstract available.
IK1-enhanced human-induced pluripotent stem cell-derived cardiomyocytes: an improved cardiomyocyte model to investigate inherited arrhythmia syndromes.
Vaidyanathan R, Markandeya YS, Kamp TJ, Makielski JC, January CT, Eckhardt LL. Vaidyanathan R, et al. Among authors: january ct. Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1611-21. doi: 10.1152/ajpheart.00481.2015. Epub 2016 Apr 8. Am J Physiol Heart Circ Physiol. 2016. PMID: 27059077 Free PMC article.
133 results