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Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm.
Dziedzicka D, Tewary M, Keller A, Tilleman L, Prochazka L, Östblom J, Couvreu De Deckersberg E, Markouli C, Franck S, Van Nieuwerburgh F, Spits C, Zandstra PW, Sermon K, Geens M. Dziedzicka D, et al. Among authors: tilleman l. Sci Rep. 2021 Mar 17;11(1):6137. doi: 10.1038/s41598-021-85447-4. Sci Rep. 2021. PMID: 33731744 Free PMC article.
Direct comparison of distinct naive pluripotent states in human embryonic stem cells.
Warrier S, Van der Jeught M, Duggal G, Tilleman L, Sutherland E, Taelman J, Popovic M, Lierman S, Chuva De Sousa Lopes S, Van Soom A, Peelman L, Van Nieuwerburgh F, De Coninck DIM, Menten B, Mestdagh P, Van de Sompele J, Deforce D, De Sutter P, Heindryckx B. Warrier S, et al. Among authors: tilleman l. Nat Commun. 2017 Apr 21;8:15055. doi: 10.1038/ncomms15055. Nat Commun. 2017. PMID: 28429706 Free PMC article.
Transcriptional landscape changes during human embryonic stem cell derivation.
Warrier S, Taelman J, Tilleman L, Van der Jeught M, Duggal G, Lierman S, Popovic M, Van Soom A, Peelman L, Van Nieuwerburgh F, Deforce D, Chuva de Sousa Lopes SM, De Sutter P, Heindryckx B. Warrier S, et al. Among authors: tilleman l. Mol Hum Reprod. 2018 Nov 1;24(11):543-555. doi: 10.1093/molehr/gay039. Mol Hum Reprod. 2018. PMID: 30239859
WNT Inhibition and Increased FGF Signaling Promotes Derivation of Less Heterogeneous Primed Human Embryonic Stem Cells, Compatible with Differentiation.
Taelman J, Popovic M, Bialecka M, Tilleman L, Warrier S, Van Der Jeught M, Menten B, Deforce D, De Sutter P, Van Nieuwerburgh F, Abe K, Heindryckx B, Chuva de Sousa Lopes SM. Taelman J, et al. Among authors: tilleman l. Stem Cells Dev. 2019 May 1;28(9):579-592. doi: 10.1089/scd.2018.0199. Epub 2019 Apr 2. Stem Cells Dev. 2019. PMID: 30827199
Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.
Markouli C, Couvreu De Deckersberg E, Regin M, Nguyen HT, Zambelli F, Keller A, Dziedzicka D, De Kock J, Tilleman L, Van Nieuwerburgh F, Franceschini L, Sermon K, Geens M, Spits C. Markouli C, et al. Among authors: tilleman l. Stem Cell Reports. 2019 Jul 9;13(1):163-176. doi: 10.1016/j.stemcr.2019.05.005. Epub 2019 Jun 6. Stem Cell Reports. 2019. PMID: 31178415 Free PMC article.
A multi-omics analysis of the grapevine pathogen Lasiodiplodia theobromae reveals that temperature affects the expression of virulence- and pathogenicity-related genes.
Félix C, Meneses R, Gonçalves MFM, Tilleman L, Duarte AS, Jorrín-Novo JV, Van de Peer Y, Deforce D, Van Nieuwerburgh F, Esteves AC, Alves A. Félix C, et al. Among authors: tilleman l. Sci Rep. 2019 Sep 11;9(1):13144. doi: 10.1038/s41598-019-49551-w. Sci Rep. 2019. PMID: 31511626 Free PMC article.
44 results