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Reimagining Druggability Using Chemoproteomic Platforms.
Spradlin JN, Zhang E, Nomura DK. Spradlin JN, et al. Among authors: zhang e. Acc Chem Res. 2021 Apr 6;54(7):1801-1813. doi: 10.1021/acs.accounts.1c00065. Epub 2021 Mar 18. Acc Chem Res. 2021. PMID: 33733731 Review.
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
Tong B, Spradlin JN, Novaes LFT, Zhang E, Hu X, Moeller M, Brittain SM, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK. Tong B, et al. Among authors: zhang e. ACS Chem Biol. 2020 Jul 17;15(7):1788-1794. doi: 10.1021/acschembio.0c00348. Epub 2020 Jun 25. ACS Chem Biol. 2020. PMID: 32568522 Free PMC article.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, Frank AO, Fuller D, Estes AR, Randal KL, Panidapu A, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Henning NJ, et al. Among authors: zhang e. Nat Chem Biol. 2022 Apr;18(4):412-421. doi: 10.1038/s41589-022-00971-2. Epub 2022 Feb 24. Nat Chem Biol. 2022. PMID: 35210618 Free PMC article.
3,049 results