Rock DA - Search Results

1

Universal Automated Immunoaffinity Purification-CE-MS Platform for Accelerating Next Generation Biologic Design.

Han M, Wang Y, Cook K, Bala N, Soto M, Rock DA, Pearson JT, Rock BM. Han M, et al. Among authors: rock da. Anal Chem. 2021 Apr 6;93(13):5562-5569. doi: 10.1021/acs.analchem.1c00149. Epub 2021 Mar 25. Anal Chem. 2021. PMID: 33764735

2

Intact mass analysis of monoclonal antibodies by capillary electrophoresis-Mass spectrometry.

Han M, Rock BM, Pearson JT, Rock DA. Han M, et al. Among authors: rock bm, rock da. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:24-32. doi: 10.1016/j.jchromb.2015.12.045. Epub 2015 Dec 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26751590

3

Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study therapeutic protein stability in vivo.

Han M, Pearson JT, Wang Y, Winters D, Soto M, Rock DA, Rock BM. Han M, et al. Among authors: rock bm, rock da. Anal Biochem. 2017 Dec 15;539:118-126. doi: 10.1016/j.ab.2017.10.005. Epub 2017 Oct 10. Anal Biochem. 2017. PMID: 29029979

4

Capillary Electrophoresis-Mass Spectrometry (CE-MS) by Sheath-Flow Nanospray Interface and Its Use in Biopharmaceutical Applications.

Han M, Smith R, Rock DA. Han M, et al. Among authors: rock da. Methods Mol Biol. 2022;2531:15-47. doi: 10.1007/978-1-0716-2493-7_2. Methods Mol Biol. 2022. PMID: 35941476

5

Bioanalytical approaches to assess the proteolytic stability of therapeutic fusion proteins.

Pearson JT, Rock DA. Pearson JT, et al. Among authors: rock da. Bioanalysis. 2015 Dec;7(23):3035-51. doi: 10.4155/bio.15.217. Epub 2015 Nov 30. Bioanalysis. 2015. PMID: 26617274 Review.

6

The combination of chemical and antibody inhibitors for superior P450 3A inhibition in reaction phenotyping studies.

Rock DA, Foti RS, Pearson JT. Rock DA, et al. Drug Metab Dispos. 2008 Dec;36(12):2410-3. doi: 10.1124/dmd.108.023572. Epub 2008 Sep 2. Drug Metab Dispos. 2008. PMID: 18765682

7

SRM-based measurements of proprotein convertase subtilisin/kexin type 9 and lipoprotein(a) kinetics in nonhuman primate serum.

Xie F, Emery MG, Gibbs JP, Rock DA, Rock BM. Xie F, et al. Among authors: rock bm, rock da. Bioanalysis. 2016 Dec;8(24):2551-2563. doi: 10.4155/bio-2016-0146. Bioanalysis. 2016. PMID: 27884075

8

Preclinical characterization of the ADME properties of a surrogate anti-IL-36R monoclonal antibody antagonist in mouse serum and tissues.

Conner KP, Pastuskovas CV, Soto M, Thomas VA, Wagner M, Rock DA. Conner KP, et al. Among authors: rock da. MAbs. 2020 Jan-Dec;12(1):1746520. doi: 10.1080/19420862.2020.1746520. MAbs. 2020. PMID: 32310023 Free PMC article.

9

Evaluation of near infrared fluorescent labeling of monoclonal antibodies as a tool for tissue distribution.

Conner KP, Rock BM, Kwon GK, Balthasar JP, Abuqayyas L, Wienkers LC, Rock DA. Conner KP, et al. Among authors: rock bm, rock da. Drug Metab Dispos. 2014 Nov;42(11):1906-13. doi: 10.1124/dmd.114.060319. Epub 2014 Sep 10. Drug Metab Dispos. 2014. PMID: 25209366 Free PMC article.

10

In vitro characterization of the drug-drug interaction potential of catabolites of antibody-maytansinoid conjugates.

Davis JA, Rock DA, Wienkers LC, Pearson JT. Davis JA, et al. Among authors: rock da. Drug Metab Dispos. 2012 Oct;40(10):1927-34. doi: 10.1124/dmd.112.046169. Epub 2012 Jun 29. Drug Metab Dispos. 2012. PMID: 22752008

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