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591 results

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Page 1
Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors.
Chou DB, Furlong BA, Posey RR, Kyprianou C, O'Sullivan LR, David R, Randle SJ, Polanska UM, Travers J, Urosevic J, Hutchinson JN, Che J, Howley AM, Hasserjian RP, Prantil-Baun R, Ingber DE. Chou DB, et al. Among authors: travers j. Nat Commun. 2022 Oct 12;13(1):6021. doi: 10.1038/s41467-022-33672-4. Nat Commun. 2022. PMID: 36224199 Free PMC article.
Cancer: drug-tolerant insurgents.
Workman P, Travers J. Workman P, et al. Among authors: travers j. Nature. 2010 Apr 8;464(7290):844-5. doi: 10.1038/464844a. Nature. 2010. PMID: 20376142 No abstract available.
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
McCoull W, Boyd S, Brown MR, Coen M, Collingwood O, Davies NL, Doherty A, Fairley G, Goldberg K, Hardaker E, He G, Hennessy EJ, Hopcroft P, Hodgson G, Jackson A, Jiang X, Karmokar A, Lainé AL, Lindsay N, Mao Y, Markandu R, McMurray L, McLean N, Mooney L, Musgrove H, Nissink JWM, Pflug A, Reddy VP, Rawlins PB, Rivers E, Schimpl M, Smith GF, Tentarelli S, Travers J, Troup RI, Walton J, Wang C, Wilkinson S, Williamson B, Winter-Holt J, Yang D, Zheng Y, Zhu Q, Smith PD. McCoull W, et al. Among authors: travers j. J Med Chem. 2021 Sep 23;64(18):13524-13539. doi: 10.1021/acs.jmedchem.1c00920. Epub 2021 Sep 3. J Med Chem. 2021. PMID: 34478292
Near-zero-index ultra-fast pulse characterization.
Jaffray W, Belli F, Carnemolla EG, Dobas C, Mackenzie M, Travers J, Kar AK, Clerici M, DeVault C, Shalaev VM, Boltasseva A, Ferrera M. Jaffray W, et al. Among authors: travers j. Nat Commun. 2022 Jun 20;13(1):3536. doi: 10.1038/s41467-022-31151-4. Nat Commun. 2022. PMID: 35725983 Free PMC article.
A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.
Rayter S, Elliott R, Travers J, Rowlands MG, Richardson TB, Boxall K, Jones K, Linardopoulos S, Workman P, Aherne W, Lord CJ, Ashworth A. Rayter S, et al. Among authors: travers j. Oncogene. 2008 Feb 14;27(8):1036-44. doi: 10.1038/sj.onc.1210729. Epub 2007 Aug 13. Oncogene. 2008. PMID: 17700519
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival.
Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG Jr. Oser MG, et al. Among authors: travers j. Cancer Discov. 2019 Feb;9(2):230-247. doi: 10.1158/2159-8290.CD-18-0389. Epub 2018 Oct 29. Cancer Discov. 2019. PMID: 30373918 Free PMC article.
Epigenetics: Targeting leukemia on the DOT.
Travers J, Blagg J, Workman P. Travers J, et al. Nat Chem Biol. 2011 Aug 28;7(10):663-5. doi: 10.1038/nchembio.661. Nat Chem Biol. 2011. PMID: 21873997 No abstract available.
Shock about heat shock in cancer.
de Billy E, Travers J, Workman P. de Billy E, et al. Among authors: travers j. Oncotarget. 2012 Aug;3(8):741-3. doi: 10.18632/oncotarget.646. Oncotarget. 2012. PMID: 22964629 Free PMC article.
591 results