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Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG. Kottke T, et al. Among authors: borad mj. Nat Commun. 2021 Mar 26;12(1):1930. doi: 10.1038/s41467-021-22115-1. Nat Commun. 2021. PMID: 33772027 Free PMC article.
Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates.
Jenks N, Myers R, Greiner SM, Thompson J, Mader EK, Greenslade A, Griesmann GE, Federspiel MJ, Rakela J, Borad MJ, Vile RG, Barber GN, Meier TR, Blanco MC, Carlson SK, Russell SJ, Peng KW. Jenks N, et al. Among authors: borad mj. Hum Gene Ther. 2010 Apr;21(4):451-62. doi: 10.1089/hum.2009.111. Hum Gene Ther. 2010. PMID: 19911974 Free PMC article.
Phase I/II Randomized Trial of Sorafenib and Bevacizumab as First-Line Therapy in Patients with Locally Advanced or Metastatic Hepatocellular Carcinoma: North Central Cancer Treatment Group Trial N0745 (Alliance).
Hubbard JM, Mahoney MR, Loui WS, Roberts LR, Smyrk TC, Gatalica Z, Borad M, Kumar S, Alberts SR. Hubbard JM, et al. Target Oncol. 2017 Apr;12(2):201-209. doi: 10.1007/s11523-016-0467-0. Target Oncol. 2017. PMID: 27943153 Free PMC article. Clinical Trial.
Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers.
Nagalo BM, Breton CA, Zhou Y, Arora M, Bogenberger JM, Barro O, Steele MB, Jenks NJ, Baker AT, Duda DG, Roberts LR, Russell SJ, Peng KW, Borad MJ. Nagalo BM, et al. Among authors: borad mj. Mol Ther Oncolytics. 2020 Sep 25;18:546-555. doi: 10.1016/j.omto.2020.08.007. Epub 2020 Aug 19. Mol Ther Oncolytics. 2020. PMID: 32839735 Free PMC article.
234 results