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Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856.
Perreault S, Chandrasekhar J, Cui ZH, Evarts J, Hao J, Kaplan JA, Kashishian A, Keegan KS, Kenney T, Koditek D, Lad L, Lepist EI, McGrath ME, Patel L, Phillips B, Therrien J, Treiberg J, Yahiaoui A, Phillips G. Perreault S, et al. Among authors: cui zh. J Med Chem. 2017 Feb 23;60(4):1555-1567. doi: 10.1021/acs.jmedchem.6b01821. Epub 2017 Feb 7. J Med Chem. 2017. PMID: 28106991
The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting β 2-adrenoceptor agonist in preclinical animal species.
Salmon M, Tannheimer SL, Gentzler TT, Cui ZH, Sorensen EA, Hartsough KC, Kim M, Purvis LJ, Barrett EG, McDonald JD, Rudolph K, Doyle-Eisele M, Kuehl PJ, Royer CM, Baker WR, Phillips GB, Wright CD. Salmon M, et al. Among authors: cui zh. Pharmacol Res Perspect. 2014 Aug;2(4):e00046. doi: 10.1002/prp2.46. Epub 2014 Jun 9. Pharmacol Res Perspect. 2014. PMID: 25505595 Free PMC article.
Planar Pentacoordinate Halogens.
Cui LJ, Miao LH, Orozco-Ic M, Li L, Pan S, Merino G, Cui ZH. Cui LJ, et al. Among authors: cui zh. Angew Chem Int Ed Engl. 2024 Nov 4:e202416057. doi: 10.1002/anie.202416057. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39494717
Planar Tetracoordinate Silicon in Si3Cu3 - Cluster.
Yin XH, Zeng HL, Liu XB, Xu XL, Xu HG, Merino G, Zheng WJ, Cui ZH. Yin XH, et al. Among authors: cui zh. Angew Chem Int Ed Engl. 2024 Oct 4:e202415789. doi: 10.1002/anie.202415789. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39363716
261 results