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Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels.
Wu MM, Liang C, Yu XD, Song BL, Yue Q, Zhai YJ, Linck V, Cai YX, Niu N, Yang X, Zhang BL, Wang QS, Zou L, Zhang S, Thai TL, Ma J, Sutliff RL, Zhang ZR, Ma HP. Wu MM, et al. Among authors: zhang bl, zhang s, zhang zr. Br J Pharmacol. 2019 Sep;176(18):3695-3711. doi: 10.1111/bph.14775. Epub 2019 Jul 30. Br J Pharmacol. 2019. PMID: 31222723 Free PMC article.
Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
Zhai YJ, Wu MM, Linck VA, Zou L, Yue Q, Wei SP, Song C, Zhang S, Williams CR, Song BL, Zhang ZR, Ma HP. Zhai YJ, et al. Among authors: zhang s, zhang zr. Biochim Biophys Acta Mol Basis Dis. 2019 Jul 1;1865(7):1915-1924. doi: 10.1016/j.bbadis.2018.08.027. Epub 2018 Sep 2. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31109455 Free article.
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