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The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.
Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. Sandoval DR, et al. Among authors: tsimikas s. bioRxiv [Preprint]. 2021 Mar 26:2021.03.22.436522. doi: 10.1101/2021.03.22.436522. bioRxiv. 2021. PMID: 33791697 Free PMC article. Preprint.
Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial.
Tomazini BM, Tramujas L, Medrado FA Junior, Gomes SPDC, Negrelli KL, Murinize GS, Santos RHN, Vianna BMP, Piotto BF, Veiga TS, Santos BRD, Peneluppi Horak AC, Lemos OMC, Lopes MA, Olicheski BB, Campones DL, Peixoto LAA, Basilio ADAC, Gebara OCE, Lopes ATA, Saconato H, Valeis N, Miranda TA, Laranjeira LN, Santucci EV, Carlin AF, Esko JD, Gordts PLSM, Tsimikas S, Cavalcanti AB. Tomazini BM, et al. Among authors: tsimikas s. PLoS One. 2024 Feb 23;19(2):e0299197. doi: 10.1371/journal.pone.0299197. eCollection 2024. PLoS One. 2024. PMID: 38394069 Free PMC article. Clinical Trial.
Oxidized Phospholipids and Calcific Aortic Valvular Disease.
Bhatia HS, Dweck MR, Craig N, Capoulade R, Pibarot P, Trainor PJ, Whelton SP, Rikhi R, Lidani KCF, Post WS, Tsai MY, Criqui MH, Shapiro MD, Budoff MJ, DeFilippis AP, Thanassoulis G, Tsimikas S. Bhatia HS, et al. Among authors: tsimikas s. J Am Coll Cardiol. 2024 Dec 17;84(25):2430-2441. doi: 10.1016/j.jacc.2024.08.070. Epub 2024 Nov 15. J Am Coll Cardiol. 2024. PMID: 39545902
The Effects of Colchicine on Lipoprotein(a) and Oxidized Phospholipid Associated Cardiovascular Disease Risk.
Mohammadnia N, van Broekhoven A, Bax WA, Eikelboom JW, Mosterd A, Fiolet ATL, Tijssen JGP, Thompson PL, de Kleijn DPV, Tsimikas S, Cornel JH, Yeang C, El Messaoudi S. Mohammadnia N, et al. Among authors: tsimikas s. Eur J Prev Cardiol. 2024 Oct 30:zwae355. doi: 10.1093/eurjpc/zwae355. Online ahead of print. Eur J Prev Cardiol. 2024. PMID: 39478683
Polygenic risk, aspirin and primary prevention of coronary artery disease.
Yu C, Natarajan P, Patel AP, Bhatia HS, Khera AV, Neumann JT, Tsimikas S, Wolfe R, Nicholls SJ, Reid CM, Zoungas S, Tonkin AM, McNeil JJ, Lacaze P. Yu C, et al. Among authors: tsimikas s. Eur Heart J Cardiovasc Pharmacother. 2024 Oct 25:pvae085. doi: 10.1093/ehjcvp/pvae085. Online ahead of print. Eur Heart J Cardiovasc Pharmacother. 2024. PMID: 39455425
383 results