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H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum.
Epigenetics Chromatin. 2021 Apr 1;14(1):19. doi: 10.1186/s13072-021-00393-9.
Epigenetics Chromatin. 2021.
PMID: 33794978
Free PMC article.
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Reader J, van der Watt ME, Taylor D, Le Manach C, Mittal N, Ottilie S, Theron A, Moyo P, Erlank E, Nardini L, Venter N, Lauterbach S, Bezuidenhout B, Horatscheck A, van Heerden A, Spillman NJ, Cowell AN, Connacher J, Opperman D, Orchard LM, Llinás M, Istvan ES, Goldberg DE, Boyle GA, Calvo D, Mancama D, Coetzer TL, Winzeler EA, Duffy J, Koekemoer LL, Basarab G, Chibale K, Birkholtz LM.
Reader J, et al. Among authors: connacher j.
Nat Commun. 2021 Jan 11;12(1):269. doi: 10.1038/s41467-020-20629-8.
Nat Commun. 2021.
PMID: 33431834
Free PMC article.
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Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
van der Watt ME, Reader J, Churchyard A, Nondaba SH, Lauterbach SB, Niemand J, Abayomi S, van Biljon RA, Connacher JI, van Wyk RDJ, Le Manach C, Paquet T, González Cabrera D, Brunschwig C, Theron A, Lozano-Arias S, Rodrigues JFI, Herreros E, Leroy D, Duffy J, Street LJ, Chibale K, Mancama D, Coetzer TL, Birkholtz LM.
van der Watt ME, et al. Among authors: connacher ji.
J Antimicrob Chemother. 2018 May 1;73(5):1279-1290. doi: 10.1093/jac/dky008.
J Antimicrob Chemother. 2018.
PMID: 29420756
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Histone Modification Landscapes as a Roadmap for Malaria Parasite Development.
Connacher J, von Grüning H, Birkholtz L.
Connacher J, et al.
Front Cell Dev Biol. 2022 Apr 1;10:848797. doi: 10.3389/fcell.2022.848797. eCollection 2022.
Front Cell Dev Biol. 2022.
PMID: 35433676
Free PMC article.
Review.
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