Llinás M - Search Results

1

H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum.

Connacher J, Josling GA, Orchard LM, Reader J, Llinás M, Birkholtz LM. Connacher J, et al. Among authors: llinas m. Epigenetics Chromatin. 2021 Apr 1;14(1):19. doi: 10.1186/s13072-021-00393-9. Epigenetics Chromatin. 2021. PMID: 33794978 Free PMC article.

2

Exploring functional genomics for drug target and therapeutics discovery in Plasmodia.

Birkholtz L, van Brummelen AC, Clark K, Niemand J, Maréchal E, Llinás M, Louw AI. Birkholtz L, et al. Among authors: llinas m. Acta Trop. 2008 Feb;105(2):113-23. doi: 10.1016/j.actatropica.2007.10.013. Epub 2007 Nov 12. Acta Trop. 2008. PMID: 18083131 Review.

3

Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses.

van Brummelen AC, Olszewski KL, Wilinski D, Llinás M, Louw AI, Birkholtz LM. van Brummelen AC, et al. Among authors: llinas m. J Biol Chem. 2009 Feb 13;284(7):4635-46. doi: 10.1074/jbc.M807085200. Epub 2008 Dec 10. J Biol Chem. 2009. PMID: 19073607 Free PMC article.

4

Sexual development in Plasmodium parasites: knowing when it's time to commit.

Josling GA, Llinás M. Josling GA, et al. Among authors: llinas m. Nat Rev Microbiol. 2015 Sep;13(9):573-87. doi: 10.1038/nrmicro3519. Nat Rev Microbiol. 2015. PMID: 26272409 Review.

5

Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast.

Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY, McFadden GI. Shears MJ, et al. Among authors: llinas m. Cell Microbiol. 2017 Jan;19(1):e12633. doi: 10.1111/cmi.12633. Epub 2016 Aug 1. Cell Microbiol. 2017. PMID: 27324409 Free PMC article.

6

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites.

Coetzee N, Sidoli S, van Biljon R, Painter H, Llinás M, Garcia BA, Birkholtz LM. Coetzee N, et al. Among authors: llinas m. Sci Rep. 2017 Apr 4;7(1):607. doi: 10.1038/s41598-017-00687-7. Sci Rep. 2017. PMID: 28377601 Free PMC article.

7

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum.

Painter HJ, Carrasquilla M, Llinás M. Painter HJ, et al. Among authors: llinas m. Genome Res. 2017 Jun;27(6):1074-1086. doi: 10.1101/gr.217356.116. Epub 2017 Apr 17. Genome Res. 2017. PMID: 28416533 Free PMC article.

8

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor.

Santos JM, Josling G, Ross P, Joshi P, Orchard L, Campbell T, Schieler A, Cristea IM, Llinás M. Santos JM, et al. Among authors: llinas m. Cell Host Microbe. 2017 Jun 14;21(6):731-741.e10. doi: 10.1016/j.chom.2017.05.006. Cell Host Microbe. 2017. PMID: 28618269 Free PMC article.

9

Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum.

Ngwa CJ, Kiesow MJ, Papst O, Orchard LM, Filarsky M, Rosinski AN, Voss TS, Llinás M, Pradel G. Ngwa CJ, et al. Among authors: llinas m. Front Cell Infect Microbiol. 2017 Jul 24;7:320. doi: 10.3389/fcimb.2017.00320. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 28791254 Free PMC article.

10

Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site.

Gisselberg JE, Herrera Z, Orchard LM, Llinás M, Yeh E. Gisselberg JE, et al. Among authors: llinas m. Cell Chem Biol. 2018 Feb 15;25(2):185-193.e5. doi: 10.1016/j.chembiol.2017.11.010. Epub 2017 Dec 21. Cell Chem Biol. 2018. PMID: 29276048 Free PMC article.

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