Ahmed HEA - Search Results

1

Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability.

Ihmaid SK, Alraqa SY, Aouad MR, Aljuhani A, Elbadawy HM, Salama SA, Rezki N, Ahmed HEA. Ihmaid SK, et al. Among authors: ahmed hea. Bioorg Chem. 2021 Jun;111:104835. doi: 10.1016/j.bioorg.2021.104835. Epub 2021 Mar 22. Bioorg Chem. 2021. PMID: 33798850

2

Self Organizing Map-Based Classification of Cathepsin k and S Inhibitors with Different Selectivity Profiles Using Different Structural Molecular Fingerprints: Design and Application for Discovery of Novel Hits.

Ihmaid SK, Ahmed HE, Zayed MF, Abadleh MM. Ihmaid SK, et al. Molecules. 2016 Jan 30;21(2):175. doi: 10.3390/molecules21020175. Molecules. 2016. PMID: 26840291 Free PMC article.

3

Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor.

Zayed MF, Ihmaid SK, Ahmed HE, El-Adl K, Asiri AM, Omar AM. Zayed MF, et al. Molecules. 2017 Jan 24;22(2):188. doi: 10.3390/molecules22020188. Molecules. 2017. PMID: 28125041 Free PMC article.

4

Discovery of novel phthalimide analogs: Synthesis, antimicrobial and antitubercular screening with molecular docking studies.

Rateb HS, Ahmed HE, Ahmed S, Ihmaid S, Afifi TH. Rateb HS, et al. EXCLI J. 2016 Dec 6;15:781-796. doi: 10.17179/excli2016-654. eCollection 2016. EXCLI J. 2016. PMID: 28337109 Free PMC article.

5

Rational design, synthesis, pharmacophore modeling, and docking studies for identification of novel potent DNA-PK inhibitors.

Ihmaid S, Ahmed HEA, Al-Sheikh Ali A, Sherif YE, Tarazi HM, Riyadh SM, Zayed MF, Abulkhair HS, Rateb HS. Ihmaid S, et al. Among authors: ahmed hea. Bioorg Chem. 2017 Jun;72:234-247. doi: 10.1016/j.bioorg.2017.04.014. Epub 2017 May 2. Bioorg Chem. 2017. PMID: 28482264

6

Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents.

Ahmed HEA, Ihmaid SK, Omar AM, Shehata AM, Rateb HS, Zayed MF, Ahmed S, Elaasser MM. Ahmed HEA, et al. Among authors: ahmed s. Bioorg Chem. 2018 Feb;76:332-342. doi: 10.1016/j.bioorg.2017.11.019. Epub 2017 Dec 2. Bioorg Chem. 2018. PMID: 29227917

7

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.

Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA. Alswah M, et al. Among authors: ahmed hea. Molecules. 2017 Dec 27;23(1):48. doi: 10.3390/molecules23010048. Molecules. 2017. PMID: 29280968 Free PMC article.

8

The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization.

Ihmaid S, Ahmed HEA, Zayed MF. Ihmaid S, et al. Among authors: ahmed hea. Int J Mol Sci. 2018 Jan 30;19(2):408. doi: 10.3390/ijms19020408. Int J Mol Sci. 2018. PMID: 29385728 Free PMC article.

9

Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.

Zayed MF, Ahmed S, Ihmaid S, Ahmed HEA, Rateb HS, Ibrahim SRM. Zayed MF, et al. Among authors: ahmed hea, ahmed s. Int J Mol Sci. 2018 Jun 11;19(6):1731. doi: 10.3390/ijms19061731. Int J Mol Sci. 2018. PMID: 29891789 Free PMC article.

10

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect.

Ahmed HEA, El-Nassag MAA, Hassan AH, Okasha RM, Ihmaid S, Fouda AM, Afifi TH, Aljuhani A, El-Agrody AM. Ahmed HEA, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1074-1088. doi: 10.1080/14756366.2018.1476503. J Enzyme Inhib Med Chem. 2018. PMID: 29923425 Free PMC article.

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