Neumaier B - Search Results

1

Species Differences in Microsomal Metabolism of Xanthine-Derived A₁ Adenosine Receptor Ligands.

Schneider D, Bier D, Holschbach M, Bauer A, Neumaier B. Schneider D, et al. Among authors: neumaier b. Pharmaceuticals (Basel). 2021 Mar 18;14(3):277. doi: 10.3390/ph14030277. Pharmaceuticals (Basel). 2021. PMID: 33803861 Free PMC article.

2

Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A₁ Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX).

Holschbach MH, Bier D, Sihver W, Schulze A, Neumaier B. Holschbach MH, et al. Among authors: neumaier b. ChemMedChem. 2017 May 22;12(10):770-784. doi: 10.1002/cmdc.201600592. Epub 2017 May 4. ChemMedChem. 2017. PMID: 28217962

3

Convenient Preparation of ¹⁸F-Labeled Peptide Probes for Potential Claudin-4 PET Imaging.

Feni L, Omrane MA, Fischer M, Zlatopolskiy BD, Neumaier B, Neundorf I. Feni L, et al. Among authors: neumaier b. Pharmaceuticals (Basel). 2017 Dec 18;10(4):99. doi: 10.3390/ph10040099. Pharmaceuticals (Basel). 2017. PMID: 29258264 Free PMC article.

4

Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics.

Zeng J, Guareschi R, Damre M, Cao R, Kless A, Neumaier B, Bauer A, Giorgetti A, Carloni P, Rossetti G. Zeng J, et al. Among authors: neumaier b. Int J Mol Sci. 2018 Aug 31;19(9):2588. doi: 10.3390/ijms19092588. Int J Mol Sci. 2018. PMID: 30200318 Free PMC article.

5

Role of Extracellular Loops and Membrane Lipids for Ligand Recognition in the Neuronal Adenosine Receptor Type 2A: An Enhanced Sampling Simulation Study.

Cao R, Giorgetti A, Bauer A, Neumaier B, Rossetti G, Carloni P. Cao R, et al. Among authors: neumaier b. Molecules. 2018 Oct 12;23(10):2616. doi: 10.3390/molecules23102616. Molecules. 2018. PMID: 30322034 Free PMC article.

6

Influence of incubation conditions on microsomal metabolism of xanthine-derived A₁ adenosine receptor ligands.

Schneider D, Bier D, Bauer A, Neumaier B, Holschbach M. Schneider D, et al. Among authors: neumaier b. J Pharmacol Toxicol Methods. 2019 Jan-Feb;95:16-26. doi: 10.1016/j.vascn.2018.11.005. Epub 2018 Nov 23. J Pharmacol Toxicol Methods. 2019. PMID: 30476620

7

Relevance of In Vitro Metabolism Models to PET Radiotracer Development: Prediction of In Vivo Clearance in Rats from Microsomal Stability Data.

Schneider D, Oskamp A, Holschbach M, Neumaier B, Bauer A, Bier D. Schneider D, et al. Among authors: neumaier b. Pharmaceuticals (Basel). 2019 Apr 14;12(2):57. doi: 10.3390/ph12020057. Pharmaceuticals (Basel). 2019. PMID: 31013984 Free PMC article.

8

Influence of binding affinity and blood plasma level on cerebral pharmacokinetics and PET imaging characteristics of two novel xanthine PET radioligands for the A₁ adenosine receptor.

Schneider D, Oskamp A, Holschbach M, Neumaier B, Bier D, Bauer A. Schneider D, et al. Among authors: neumaier b. Nucl Med Biol. 2020 Mar-Apr;82-83:1-8. doi: 10.1016/j.nucmedbio.2019.12.001. Epub 2019 Dec 2. Nucl Med Biol. 2020. PMID: 31838339

9

Image-Derived Input Functions for Quantification of A₁ Adenosine Receptors Availability in Mice Brains Using PET and [¹⁸F]CPFPX.

He X, Wedekind F, Kroll T, Oskamp A, Beer S, Drzezga A, Ermert J, Neumaier B, Bauer A, Elmenhorst D. He X, et al. Among authors: neumaier b. Front Physiol. 2020 Jan 29;10:1617. doi: 10.3389/fphys.2019.01617. eCollection 2019. Front Physiol. 2020. PMID: 32063864 Free PMC article.

10

Development and Evaluation of a Versatile Receptor-Ligand Binding Assay Using Cell Membrane Preparations Embedded in an Agarose Gel Matrix and Evaluation with the Human Adenosine A₁ Receptor.

Bier D, Schulze A, Holschbach M, Neumaier B, Baumann A. Bier D, et al. Among authors: neumaier b. Assay Drug Dev Technol. 2020 Oct;18(7):328-340. doi: 10.1089/adt.2020.991. Epub 2020 Jul 29. Assay Drug Dev Technol. 2020. PMID: 32749852

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