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A MAPK/miR-29 Axis Suppresses Melanoma by Targeting MAFG and MYBL2.
Vera O, Bok I, Jasani N, Nakamura K, Xu X, Mecozzi N, Angarita A, Wang K, Tsai KY, Karreth FA. Vera O, et al. Among authors: tsai ky. Cancers (Basel). 2021 Mar 19;13(6):1408. doi: 10.3390/cancers13061408. Cancers (Basel). 2021. PMID: 33808771 Free PMC article.
Evolutionary Analysis of TCGA Data Using Over- and Under- Mutated Genes Identify Key Molecular Pathways and Cellular Functions in Lung Cancer Subtypes.
Freischel AR, Teer JK, Luddy K, Cunningham J, Artzy-Randrup Y, Epstein T, Tsai KY, Berglund A, Cleveland JL, Gillies RJ, Brown JS, Gatenby RA. Freischel AR, et al. Among authors: tsai ky. Cancers (Basel). 2022 Dec 20;15(1):18. doi: 10.3390/cancers15010018. Cancers (Basel). 2022. PMID: 36612014 Free PMC article.
MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability.
Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai KY, DeNicola GM, Karreth FA. Jasani N, et al. Among authors: tsai ky. bioRxiv [Preprint]. 2024 Apr 15:2024.04.11.589139. doi: 10.1101/2024.04.11.589139. bioRxiv. 2024. Update in: Cancer Res. 2025 Jan 15;85(2):314-328. doi: 10.1158/0008-5472.CAN-24-2471 PMID: 38659816 Free PMC article. Updated. Preprint.
The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression.
Vera O, Martinez M, Soto-Vargas Z, Wang K, Xu X, Ruiz-Buceta S, Mecozzi N, Chadourne M, Posorske B, Angarita A, Bok I, Liu Q, Murikipudi H, Kim Y, Messina JL, Tsai KY, Major MB, Lau EK, Yu X, Ibanez-de-Caceres I, Karreth FA. Vera O, et al. Among authors: tsai ky. bioRxiv [Preprint]. 2024 Sep 6:2024.09.03.611024. doi: 10.1101/2024.09.03.611024. bioRxiv. 2024. PMID: 39282450 Free PMC article. Preprint.
miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3.
Chitsazzadeh V, Nguyen TN, de Mingo Pulido A, Bittencourt BB, Du L, Adelmann CH, Ortiz Rivera I, Nguyen KA, Guerra LD, Davis A, Napoli M, Ma W, Davis RE, Rajapakshe K, Coarfa C, Flores ER, Tsai KY. Chitsazzadeh V, et al. Among authors: tsai ky. J Invest Dermatol. 2022 Jul;142(7):1956-1965.e2. doi: 10.1016/j.jid.2021.09.040. Epub 2021 Dec 8. J Invest Dermatol. 2022. PMID: 34890627 Free PMC article.
MicroRNA heterogeneity in melanoma progression.
Thyagarajan A, Tsai KY, Sahu RP. Thyagarajan A, et al. Among authors: tsai ky. Semin Cancer Biol. 2019 Dec;59:208-220. doi: 10.1016/j.semcancer.2019.05.021. Epub 2019 Jun 1. Semin Cancer Biol. 2019. PMID: 31163254 Free PMC article. Review.
Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation.
Napoli M, Li X, Ackerman HD, Deshpande AA, Barannikov I, Pisegna MA, Bedrosian I, Mitsch J, Quinlan P, Thompson A, Rajapakshe K, Coarfa C, Gunaratne PH, Marchion DC, Magliocco AM, Tsai KY, Flores ER. Napoli M, et al. Among authors: tsai ky. Nat Commun. 2020 Oct 14;11(1):5156. doi: 10.1038/s41467-020-18973-w. Nat Commun. 2020. PMID: 33056990 Free PMC article.
256 results