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C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.
Fumagalli L, Young FL, Boeynaems S, De Decker M, Mehta AR, Swijsen A, Fazal R, Guo W, Moisse M, Beckers J, Dedeene L, Selvaraj BT, Vandoorne T, Madan V, van Blitterswijk M, Raitcheva D, McCampbell A, Poesen K, Gitler AD, Koch P, Vanden Berghe P, Thal DR, Verfaillie C, Chandran S, Van Den Bosch L, Bullock SL, Van Damme P. Fumagalli L, et al. Among authors: thal dr. Sci Adv. 2021 Apr 9;7(15):eabg3013. doi: 10.1126/sciadv.abg3013. Print 2021 Apr. Sci Adv. 2021. PMID: 33837088 Free PMC article.
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study.
Van Weehaeghe D, Van Schoor E, De Vocht J, Koole M, Attili B, Celen S, Declercq L, Thal DR, Van Damme P, Bormans G, Van Laere K. Van Weehaeghe D, et al. Among authors: thal dr. J Nucl Med. 2020 Apr;61(4):604-607. doi: 10.2967/jnumed.119.231985. Epub 2019 Sep 27. J Nucl Med. 2020. PMID: 31562223 Free PMC article.
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic-pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases.
Dedeene L, Van Schoor E, Ospitalieri S, Ronisz A, Weishaupt JH, Otto M, Ludolph AC, Scheuerle A, Vandenberghe R, Van Damme P, Poesen K, Thal DR. Dedeene L, et al. Among authors: thal dr. Acta Neuropathol. 2020 Nov;140(5):777-781. doi: 10.1007/s00401-020-02216-9. Epub 2020 Aug 30. Acta Neuropathol. 2020. PMID: 32862270 No abstract available.
Necrosome-positive granulovacuolar degeneration is associated with TDP-43 pathological lesions in the hippocampus of ALS/FTLD cases.
Van Schoor E, Koper MJ, Ospitalieri S, Dedeene L, Tomé SO, Vandenberghe R, Brenner D, Otto M, Weishaupt J, Ludolph AC, Van Damme P, Van Den Bosch L, Thal DR. Van Schoor E, et al. Among authors: thal dr. Neuropathol Appl Neurobiol. 2021 Feb;47(2):328-345. doi: 10.1111/nan.12668. Epub 2020 Oct 20. Neuropathol Appl Neurobiol. 2021. PMID: 32949047
256 results