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Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.
Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Among authors: flotte tr. Nat Methods. 2012 Mar 4;9(4):403-9. doi: 10.1038/nmeth.1903. Nat Methods. 2012. PMID: 22388288 Free PMC article.
Gene transfer in the lung using recombinant adeno-associated virus.
Gruntman AM, Mueller C, Flotte TR, Gao G. Gruntman AM, et al. Among authors: flotte tr. Curr Protoc Microbiol. 2012 Aug;Chapter 14:Unit14D.2. doi: 10.1002/9780471729259.mc14d02s26. Curr Protoc Microbiol. 2012. PMID: 22875566 Free PMC article.
A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.
Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, Matalon R, Gao G. Ahmed SS, et al. Among authors: flotte tr. Mol Ther. 2013 Dec;21(12):2136-47. doi: 10.1038/mt.2013.138. Epub 2013 Jul 2. Mol Ther. 2013. PMID: 23817205 Free PMC article.
Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?
Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A. Berns KI, et al. Among authors: flotte tr. Hum Gene Ther. 2015 Dec;26(12):779-81. doi: 10.1089/hum.2015.29014.kib. Hum Gene Ther. 2015. PMID: 26690810 Free PMC article. No abstract available.
318 results